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Full Description
Chronic kidney disease is a global major health issue that ultimately leads to end-stage renal disease, a devastating condition requiring costly renal replacement therapy. Given this background, extensive understanding of the pathogenesis of the disease and exploring novel therapeutic targets will help to alleviate disease progression, improve prognosis and reduce its impact on the global economic burden. Currently, primary glomerulonephritis is the leading cause of chronic kidney disease and end-stage renal disease in China and many other countries. Recently, there has been much progress with regard to pathogenesis as well as treatment of primary glomerulonephritis. Clinical data from Chinese studies have significantly contributed to the making of international guidelines and histological classifications of the disease. This book focuses on the cutting-edge knowledge and provides up-to-date information on primary glomerulonephritis. Topics covered are IgA nephropathy, focal segmental glomerulosclerosis, membranous nephropathy, membranoproliferative glomerulonephritis, and crescentic glomerulonephritis.
Contents
Preface: Chen, N.; Overview; Primary Glomerulonephritis in Mainland China: An Overview: Xie, J.; Chen, N.; Advances in the Pathology of Glomerular Diseases: Weening, J.J.; Ronco, P.; Remuzzi, G.; Changing Spectrum of Biopsy-Proven Primary Glomerular Diseases over the Past 15 Years: A Single-Center Study in China: Pan, X.; Xu, J.; Ren, H.; Zhang, W.; Xu, Y.; Shen, P.; Li, X.; Wang, W.; Chen, X.; Wu, P.; Feng, X.; Hao, C.; Chen, N.; Evaluation of Anemia and Serum iPTH, Calcium, and Phosphorus in Patients with Primary Glomerulonephritis: Li, Y.; Zhang, W.; Ren, H.; Wang, W.; Shi, H.; Li, X.; Chen, X.; Shen, P.; Wu, X.; Xie, J.; Chen, N.; IgA Nephropathy; Role of Podocyte Injury in IgA Nephropathy: Menon, M.C.; Chuang, P.Y.; He, J.C.; Genetic Studies of IgA Nephropathy: What Have We Learned from Genome-Wide Association Studies: Xie, J.; Shapiro, S.; Gharavi, A.; Immunopathological Predictors of Prognosis in IgA Nephropathy: Tomino, Y.; Treatment of Progressive IgA Nephropathy: An Update: Wang, W.; Chen, N.; Focal Segmental Glomerulosclerosis/Minimal Change Disease; Different Targets for Treating Focal Segmental Glomerular Sclerosis: Coppo, R.; Screening of ACTN4 and TRPC6 Mutations in a Chinese Cohort of Patients with Adult-Onset Familial Focal Segmental Glomerulosclerosis: Zhang, Q.; Ma, J.; Xie, J.; Wang, Z.; Zhu, B.; Hao, X.; Yang, L.; Ren, H.; Chen, N.; Increased Risk of Treatment Failure and End-Stage Renal Disease in Familial Focal Segmental Glomerular Sclerosis: Hao, X.; Xie, J.; Ma, J.; Wang, Z.; Zhou, Q.; Yang, L.; Pan, X.; Ren, H.; Chen, N.; Treatment and Prognosis of Primary Focal Segmental Glomerulosclerosis: Ren, H.; Shen, P.; Li, X.; Pan, X.; Zhang, Q.; Feng, X.; Zhang, W.; Chen, N.; New Insights into Treatment of Nephrotic Syndrome in Children: Wang, X.; Xu, H.; Membranous Nephropathy; Pathogenesis of Membranous Nephropathy: A New Paradigm in Evolution: Glassock, R.J.; Short-Term Complications of Membranous Nephropathy: Barbour, S.; Reich, H.; Cattran, D.; Tacrolimus Combined with Corticosteroids in Idiopathic Membranous Nephropathy: A Randomized, Prospective, Controlled Trial: Xu, J.; Zhang, W.; Xu, Y.; Shen, P.; Ren, H.; Wang, W.; Li, X.; Pan, X.; Chen, N.; Membranoproliferative Glomerulonephritis; Membranoproliferative Glomerulonephritis - Mechanisms and Treatment: Appel, G.B.; Re-Evaluation of the Classification System for Membranoproliferative Glomerulonephritis: Lu, Y.; Shen, P.; Li, X.; Xu, Y.; Pan, X.; Wang, W.; Chen, X.; Zhang, W.; Ren, H.; Chen, N.; C3 Glomerulopathy: Servais, A.; Noel, L.-H.; Fremeaux-Bacchi, V.; Lesavre, P.; Hepatitis C Virus-Associated Glomerulonephritis: Tang, S.C.W.; Lai, K.N.; Crescentic Glomerulonephritis; Pathogenesis of Rapidly Progressive Glomerulonephritis: What Do We Learn? Chen, Y.-X.; Chen, N.; ANCA-Associated Renal Vasculitis - An Update: Tesar, V.; Hruskova, Z.; Management of Crescentic Glomerulonephritis: What Are the Recent Advances? Li, X.; Chen, N.; Plasma Exchange in the Treatment of Rapidly Progressive Glomerulonephritis: Chen, X.; Chen, N.
