基本説明
Special Topics Issue: 'Neurodegenerative Diseases 2012, Vol. 10, No. 1-4'.
Full Description
This special topic issue of 'Neurodegenerative Diseases' contains contributions discussing the subject in-depth. 'Neurodegenerative Diseases' is a well-respected, international peer-reviewed journal in Neurobiology. Special topic issues are included in the subscription.
Contents
Nobel Lecture; Intracellular Protein Degradation: From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting: Ciechanover, A.; Biology of Neurodegeneration; Wnt-5a Is a Synaptogenic Factor with Neuroprotective Properties against A[beta] Toxicity: Varela-Nallar L. et al.; Intraneuronal A[beta] Accumulation, Amyloid Plaques, and Synapse Pathology in Alzheimer's Disease: Capetillo-Zarate et al.; Tau Overexpression Results in Its Secretion via Membrane Vesicles: Simon, D. et al.; Microglial Activation in Neuroinflammation: Implications for the Etiology of Neurodegeneration: Kaneko, Y.S.et al.; Retromers in Alzheimer's Disease: Siegenthaler, B.M.; Rajendran, L.; Clinical Studies and Observations; Effects of Exercise and B Vitamins on Homocysteine and Glutathione in Parkinson's Disease: A Randomized Trial: DiFrancisco-Donoghue, J. et al.; Evaluation of the Performance of Novel A[beta] Isoforms as Theragnostic Markers in Alzheimer's Disease: From the Cell to the Patient: Portelius, E. et al.; Software Tool for Improved Prediction of Alzheimer's Disease: Soininen, H. et al.; Cortical Brain Biopsy in Long-Term Prognostication of 468 Patients with Possible Normal Pressure Hydrocephalus: Leinonen, V. et al.; Towards Defining a Rigidity-Associated Pathogenic Pathway in Idiopathic Parkinsonism: Dobbs, R.J. et al.; Imaging, Biomarkers, Genetics, and Diagnostic Markers; Cognitive Function in Health and Disease: The Role of Epigenetic Mechanisms: Mungenast, A.E.; Tsai, L.-H.; Pin1 Contribution to Alzheimer's Disease: Transcriptional and Epigenetic Mechanisms in Patients with Late-Onset Alzheimer's Disease: Arosio, B.et al.; Activation of the Unfolded Protein Response Is an Early Event in Alzheimer's and Parkinson's Disease: Hoozemans, J.J.M. et al.; Targeting Skp1, an Ubiquitin E3 Ligase Component Found Decreased in Sporadic Parkinson's Disease: Mandel, S.A. et al.; A Pilot Study Examining Associations between DYRK1A and [alpha]-Synuclein Dementias: Jones, E.L. et al.; Structural MRI in Normal Aging and Alzheimer's Disease: White and Black Spots: Cavalieri, M. et al.; Immunization and Innate Immunity; Innate Immunity and the Etiology of Late-Onset Alzheimer's Disease: Eikelenboom, P. et al.; Curcumins Promote Monocytic Gene Expression Related to [beta]-Amyloid and Superoxide Dismutase Clearance: Cashman, J.R. et al.; Prion Proteins, Statins, Cholesterol; [alpha]-Secretase-Derived Cleavage of Cellular Prion Yields Biologically Active Catabolites with Distinct Functions: Guillot-Sestier, M.-V.; Checler, F.; Cellular Prion Protein Mediates Toxic Signaling of Amyloid Beta: Resenberger, U.K.; Winklhofer, K.F.; Tatzelt, J.; Dual Effects of Statins on A[beta] Metabolism: Upregulation of the Degradation of APP-CTF and A[beta] Clearance: Sato, N. et al.; Cerebrovascular Lesions and Primary Neurodegenerative Diseases; Plasma [beta]-Amyloid Levels in Cerebral Amyloid Angiopathy-Associated Hemorrhagic Stroke: Hernandez-Guillamon, M. et al.; Insights into Caspase-Mediated Apoptotic Pathways Induced by Amyloid-[beta] in Cerebral Microvascular Endothelial Cells: Fossati, S. et al.; Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy: Carrano, A. et al.
