Description
This new guide on Cutaneous Metastases is crafted for healthcare professionals and offers in-depth examination of the development, diagnosis, treatment, prognosis, and survival dynamics surrounding cutaneous metastases, providing a holistic perspective on these dermatological challenges. Ensuring an encompassing approach, the book expands on the diverse landscape of primary tumors, and their dermatological implications. The introduction defines cutaneous metastases, exploring epidemiology, and the underlying pathogenesis. Dedicated chapters follow, that focus on cutaneous metastases from gynecological cancers, providing detailed insights into ovarian, cervical, and endometrial cancers. Metastases originating from gastrointestinal cancers, including liver, colorectal and pancreatic cancers, are then taken into exam, as well as those deriving from lung cancer and breast cancer (invasive ductal and invasive lobular carcinoma). Following chapters deal with other primary tumors, including prostate, kidney, and thyroid cancers. Understanding the histopathological features of cutaneous metastases is crucial; to this end, the book covers classification to immunohistochemical profiling and molecular clonal analysis, all essential for accurate diagnosis. A dedicated section outlines the various treatment options, prognosis considerations, and follow-up protocols for cutaneous metastases. Real-world cases provide clinical insights and bridge theory with practice. The book concludes with a comprehensive summary of key points and outlines future directions for research on cutaneous metastases. With its clear tone and multidisciplinary perspective on dermatological challenges posed by metastatic manifestations, this work will be a valued companion to healthcare professionals, including dermatologists, oncologists, and other specialists involved in the care of cancer patients.
Preface.- 1 Introduction.- 1.1 Definition of cutaneous metastases.- 1.2 Epidemiology of cutaneous metastases.- 1.3 Pathogenesis of cutaneous metastases.- 2. Cutaneous metastases from gynecological cancers.- 2.1 Ovarian cancer.- 2.2 Cervical cancer.- 2.3 Endometrial cancer.- 3 Cutaneous metastases from gastrointestinal cancers.- 3.1 Liver cancer.- 3.2 Colorectal cancer.- 3.3 Pancreatic cancer.- 4. Cutaneous metastases from lung cancer.- 4.1 Non-small cell lung cancer.- 4.2 Small cell lung cancer.- 5 Cutaneous metastases from breast cancer.- 5.1 Invasive ductal carcinoma.- 5.2 Invasive lobular carcinoma.- 6 Cutaneous metastases from other primary tumors.- 6.1 Prostate cancer.- 6.2 Kidney cancer.- 6.3 Thyroid cancer.- 7 Histopathology of cutaneous metastases.- 7.1 Classification of cutaneous metastases based on WHO classification for tumors.- 7.2 Immunohistochemical profiling of cutaneous metastases.- 7.3 Molecular clonal analysis of cutaneous metastases.- 8 Management of cutaneous metastases.- 8.1 Treatment options for cutaneous metastases.- 8.2 Prognosis of cutaneous metastases.- 8.3 Follow-up of patients with cutaneous metastases.- 9 Case studies.- 9.1 Case presentations of cutaneous metastases from different primary tumors.- 9.2 Discussion of management strategies for each case.- 10 Conclusion.- 10.1 Summary of key points.- 10.2 Future directions for research on cutaneous metastases.
Doctor Dimitra Koumaki is a Consultant in Dermatology and Venereology, currently working in the Dermatology Department of the University Hospital of Heraklion, Crete, Greece. She holds an MD, MSc, and PhD from the Medical School of Athens, Greece, as well as an MSc in Dermoscopy from the Aristotle University of Thessaloniki, Greece.
Additionally, she holds an interuniversity diploma in Cutaneous Tumor Surgery from the University of Versailles, France, and an interuniversity diploma (D.I.U.) in Aesthetic Dermatology, Lasers in Dermatology, and Cosmetics from the Université de Franche-Comté in Besançon, France.
She completed her medical studies in Athens, Greece, and has worked at several university hospitals in the United Kingdom, including Manchester and London, as well as at the University Hospital of Lausanne CHUV in Switzerland.
Her primary research interests include skin cancer, skin surgery, and photobiology. Dr. Koumaki has authored more than 115 scientific publications.
Dr. Marios Papadakis is Associate Professor and Head of the Department of Plastic, Reconstructive & Aesthetic Surgery at the University of Thessaly, Greece. He holds an MD and a PhD in Plastic Surgery, as well as an MBA in Healthcare Management, and is a certified Editor in the Life Sciences. His research interests include skin cancer, wound healing, stem cells, regenerative surgery, ischemia reperfusion injury, healthcare management, the history of science, and scientific writing, with particular emphasis on authorship proliferation. He has authored and co-authored over 300 peer-reviewed publications and has served as guest editor for several journal issues on a range of topics.
Doctor Stamatios Gregoriou is an associate professor of Dermatology and Venereology at the National and Kapodistrian University of Athens. His main academic interests include Atopic dermatitis, Contact dermatitis, Chronic Spontaneous Urticaria, Hyperhidrosis and Nail Disorders. He is the author of more than 300 publications in peer reviewed journals and has done editorial work for several of them. He also serves as a member in multiple European Academy of Dermatology committees and task forces.
