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Full Description
This fully updated and expanded second edition of the textbook provides an accessible overview of how the gut microbiome contributes to various aspects of human health through its connection to the immune system. Readers will gain a fundamental understanding of the composition and function of the microbiome and its critical influence on diseases and disorders such as cancer, inflammatory diseases, allergies, and metabolic and organ disorders. The authors explore the evolution of the human gut microbiome, its influence on early life development, and its relationship to diet and nutrition. In addition, the textbook discusses the latest microbiome-based therapeutic approaches. This second edition has been conceptually revised, didactically improved, and expanded by three brand-new chapters.
Aimed at medical microbiology students, researchers, and anyone interested in learning more about the impact of the gut microbiome on human health and well-being.
Contents
Intestinal Microbiome in Health and Disease: Introduction.- Composition and Function of the Human Gut Microbiome.- Microbiome and Early Life.- Sequencing-based Microbiome Profiling.- Evolutionary Perspectives on the Human Gut Microbiome.- Microbiome and Diet.- Microbiome and Gut Immunity: The Epithelium.- The interplay of the microbiome with the innate immune system.- Microbiome and Gut Immunity: T Cells.- Microbiome and Gut Immunity: B Cells.- Microbiome and Diseases: Inflammatory Bowel Diseases.- Microbiome and Diseases - Allergys.- Microbiome and Diseases: Graft-Versus-Host Disease.- Microbiome and Diseases: Infection.- Microbiome and Diseases: Colorectal Cancer.- Microbiome and Diseases: Metabolic Disorders.- Microbiome and Diseases: Steatotic liver Disease.- Microbiome and Diseases: Gut-Brain Axis and Neurological Disorders.- Clinical Diagnostics for Microbiome-based Therapies.- Fecal Microbiota Transplantation.- Gnotobiology.- Functional Metabolites from the Human Gut Microbiota.- Microbiome-based Therapies: Phage Intervention.



