Description
The book provides a tailored overview on precision medicine and targeted therapies, specifically focusing on cancer treatments. Split into three parts covering the foundations of molecular precision medicine, its application in specific cancer types, and emerging trends and future directions in the field, this book serves as a comprehensive resource for researchers, clinicians, and healthcare professionals seeking to understand and implement precision medicine in cancer. Molecular Precision Medicine in Cancer explores the fundamental principles of precision medicine, including the use of genomics and molecular profiling approaches to identify and characterize specific genetic alterations within tumors. It also provides in-depth coverage of various cancer types, discussing the unique molecular characteristics and targeted therapies associated with each. Furthermore, the book addresses the state-of-art technologies and challenges surrounding precision medicine.
Part I. Precision Medicine in Specific Cancer Type.- 1. Precision Oncology for Breast Cancer: From Molecular Insights to Personalised Therapies.- Precision Medicine in Colorectal Cancer.- 3. Precision Medicine in Liver Cancer.- 4. Precision Medicine in Prostate Cancer.- 5. Precision Medicine in Gastric, Gastroesophageal, Pancreatic, and Biliary Tract Tumors.- 6. Renal Cell Carcinoma: Integrating Histology, Multiomics, and Targeted Therapeutic Strategies.- 7. Molecular Biomarkers in Urothelial Carcinoma: Current Insights and Future Directions.- 8. Targeted Therapies and Molecular Profiling in Cervical Cancer: A Precision Medicine Perspective.- Part II. Emerging Trends and Future Directions.- 9. Microenvironmental and Metabolic Factors in Tumor Progression: A Precision Medicine Perspective.- 10. Non-coding RNAs: Therapeutic Implications in Cancers.- 11. Liquid Biopsies and Circulating Tumor DNA.- 12. Interleukin-12 Gene Therapy for Cancer Immunotherapy.- 13. The Emerging Role of Artificial Intelligence in Advancing Molecular Precision Medicine for Cancer .- 14. Drug Repurposing Strategies in the Era of Precision Oncology.
Luis María Vaschetto obtained his Ph.D. in Biological Sciences from the Universidad Nacional de Córdoba (Argentina). He was a postdoctoral researcher at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and a Research Associate at the South Dakota State University (SDSU). He has first-authored over ten academic articles in peer-reviewed, high-impact journals. Currently, he is a Consultant for several international companies and a Research Scholar at the Ronin Institute (RIIS 2.0). He also serves as Series Editor for the Book Series Epigenetics and Human Health (EHH), published by Springer Nature (Switzerland). Dr. Vaschetto has already edited and authored eleven international books, including four for the EHH series and three for Methods in Molecular Biology (MiMB, Springer Nature, USA). His research mainly focuses on understanding gene regulation mechanisms involved in plant and animal development, as well as their effects on human health and diseases
Sameer Srivastava obtained his PhD in Biotechnology from CSIR-National Chemical Laboratory, affiliated to Savitribai Phule Pune University, Pune, (India). He was awarded prestigious Endeavour Award (Govt. of Australia) to pursue his postdoctoral studies at Lowy Cancer Research Center, University of New South Wales, Sydney, Australia. Currently he is working as Associate Professor at Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, India. He has authored more than 50 research articles in various reputed international journals and also published numerous book chapters. He also has handled various government funded project in India including, DBT, India, DST, India, ICMR, India. His research mainly focuses on understanding the epigenetic mechanisms involved in colorectal cancer development and progression. Another area of research which interests him is identifying genetic and epigenetic biomarkers in early onset-CRCs.
