Description
Effective pain management remains a critical component of high quality clinical care, even as the implications of the opioid epidemic continue to unfold. This text provides a rigorous, evidence based framework for the safe use of multimodal analgesic strategies that reduce reliance on opioid therapy. Emphasizing clinical applicability, it prepares healthcare professionals to balance patient safety with the ethical imperative of adequate pain control.
The book presents a structured examination of adjunctive analgesics and their roles across diverse practice settings, integrating current research with practical guidance for implementation. In addition to pharmacologic approaches, it evaluates non pharmacologic interventions including physical, occupational, music, and art therapies highlighting their documented contributions to improved patient outcomes and functional recovery. Recognizing the complexities inherent in transitions of care, the text addresses challenges faced by underserved and vulnerable populations. These discussions reinforce the importance of coordinated, patient centered care across the healthcare continuum. Chapters on clinical cases contextualize key concepts and offer learners opportunities to apply principles to realistic scenarios.
Designed for graduate level healthcare trainees and practicing clinicians including physicians, advanced practice providers, pharmacists, dentists, and rehabilitation specialists this resource supports the development of competent, interdisciplinary, and compassionate pain management practices.
Section 1: Introduction to Pain Management and Multimodal Analgesia.- Definitions and Classifications of Pain.- Pathophysiology of Pain.- Evaluation of Pain Scales and Definitions of Outcomes Measures from Primary Literature.- Interprofessional Approach to Pain Management.- Section 2: Adjunctive Analgesics.- Acetaminophen.- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).- Gabapentinoids.- Antidepressants.- Alpha2 Agonists.- Skeletal Muscle Relaxants.- Anticonvulsants.- Ketamine.- Antipsychotics.- Calcium Channel Blockers.- Magnesium.- Lidocaine. Cannabidiol.- Compounded Pharmaceutical Products.- Management of Adverse Drug Effects for Adjunctive Analgesics.- Clinically Significant Drug-Drug Interactions.- Pain in The Older Adult.- Pain in Pediatrics.- Pain in Transgender Patients.- Ethics in Pain Management.- Section 3: Transitions of Care.- Medication Reconciliation.- Barriers to Patients Receiving Care.- Assessing Pain Health Literacy.- Managing Nonadherence.- Section 4: Adjunctive Therapies Beyond Medications.- Physical Therapy and Exercise Science.- Art Therapy.- Music Therapy.- Psychotherapy Approaches and Behavioral Modification Strategies.- Section 5: Clinical Cases.- Clinical Case: Alpha2 Agonists.- Clinical Case: Patient Barriers.- Clinical Case: Art Therapy.- Clinical Case: Medication Adherence.
Justin Reinert, Pharm.D., MBA, BCCCP
Associate Professor
The University of Toledo College of Pharmacy and Pharmaceutical Sciences
Department of Pharmacy Practice , Toledo, OH
Donald L. Branam, Pharm.D., BCPS, FASHP
Associate Professor
South College School of Pharmacy
Knoxville, TN, USA
Thomas J. Papadimos, MD, MPH, FCCM, FAIM
Professor of Anesthesiology
The University of Toledo College of Medicine and Health Sciences
Departments of Anesthesia and Critical Care, Toledo, OH
Michael A. Veronin, Ph.D.
Professor
The University of Texas at Tyler , Tyler, Texas



