Full Description
This book represents a concise and easily referred guide to be used when the need arises, so that trainees in radiology facing a Nuclear Medicine matter can cope with the same and understand how to report correctly, for instance, their first bone scan or first renogram and give them briefly the underlying physiology.
The sections of the volume are based on radiopharmaceuticals which enables the reader to understand the physiology underpinning the handling of the radiopharmaceuticals and why, therefore, they are applied to the imaging tests for which they are used. This setting will surely help radiological trainees to quickly acquire a grasp of the essentials of nuclear medicine and enable them to maximise the value of the period they spend training in nuclear medicine as part of their training.
Main goal of the book is to let understand the molecular structure and basic physiology of a radiopharmaceutical; leading to an understanding of why and how the radiopharmaceutical works in its application to different organ systems; leading to basic reporting skills and an understanding of the mistakes being made in the report; understanding the radiopharmaceutical kinetics and how they are used to quantify physiological variables in disease.
The book represents a very useful tool to trainees intending to specialise in nuclear medicine whether as nuclear medicine physicians or radionuclide radiologists.
Contents
Part I. Tracer Kinetics.- 1. Mathematical Equations.- 2. Physiological Equations.- 3. Clearance, Blood Flow And Extraction Fraction [Or Efficiency (%)].- 4. Distribution Volume And Mean Transit Time.- 5. Blood Capillary Function.- Part II. Basic Medical Statistics.- 6. Parametric Statistics.- 7. Non-Parametric Statistics.- 8. Interpretation of Statistical Significance.- Part III. Basic Sciences of Nuclear Medicine.- 9. Basic Sciences of NM.- Part IV. Tc-99m Compounds.- 10. FREE Tc-99m (Pertechnetate; Tc-99mO4; 161 Da; Half-Life 6 H).- 11. Tc-99m-Diethyltriaminepentaacetic Acid (DTPA; MW 650 Da).- 12. Tc-99m-Mercaptoacetyltriglycine (MAG3) (MW 417 Da).- 13. Tc-99m-Dimercaptosuccinic Acid (DMSA) (MW 182 Da).- 14. Tc-99m-Iminodiacetic Acid (HIDA) (MW 177 Da).- 15. Tc-99m-Labelled Diphosphonates (MW ‾300 Da).- 16. Tc-99m-Sestamibi (MW 778 Da) And Tc-99m-Tetrafosmin (MW 895 Da).- 17. Tc-99m-Hexamethylpropylamine Oxime (HMPAO) (MW 385 Da).- 18. Tc-99m-Labelled Aerosols.- 19. Tc-99m-Labelled Liquid and Semisolid Meals.- 20. Tc-99m-Labelled Red Blood Cells.- 21. Tc-99m-Labelled Proteins.- 22. Tc-99m-Labelled Nanocolloids.- Part V. Miscellaneous Radiopharmaceuticals.- 23. Noble Gases.- 24. Iodine-123 (Half-Life 13.2 H; Decays by Electron Capture To Te-123) and Iodine-131 (8.1 D, Beta Minus Emission, Xe-131).- 25. Selenium-75 (Half-Life 120 D; Decays by Electron Capture to As-75; 136, 265 and 401 Kev).- 26. Indium-111 (Half-Life 2.8 D; Decays by Electron Capture to Cd-111; 172 Kev and 245 Kev).- 27. Radionuclides of Historical Interest.- Part VI. Positron Emission Tomography (PET).- 28. Compounds Of Fluorine-18.- 29. Compounds Of Gallium 68 (Half-Life 68 Minutes).- 30. Rubidium-82 (Half-Life 78 Sec).
