Full Description
This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to standardized and emerging technologies and probe designs for different modalities, such as PET, SPECT, optical and optoacoustic imaging, ultrasound, CT, and MRI. The second section focuses on multiscale preclinical applications ranging from advanced microscopy and mass spectroscopy to whole-body imaging. In the third section, various clinical applications are presented, including image-guided surgery and the radiomic analysis of multiple imaging features. The final two sections are dedicated to the emerging, crucial role that molecular imaging can play in the planning and monitoring of external and internal radiotherapy, and to future challenges and prospects in multimodality imaging. Given its scope, the handbook will benefit all readers who are interested in the revolution in diagnostic and therapeutic oncology that is now being brought about by molecular imaging.
Contents
Part 1: Technology and Probe Design 1 Advanced X-ray Imaging Technology.- 2 Computed Tomography and Magnetic Resonance Imaging.- 3 (Hybrid) SPECT and PET Technologies.- 4 Total Body PET.- 5 Ultrasound Imaging.- 6 Optical and Optoacoustic Imaging.- 7 Multifunctional Magnetic Resonance Imaging Probes.- 8 Single Photon Emission Computed Tomography Tracer.- 9 F-Labeled Small-Molecule and Low-Molecular-Weight PET Tracers for the Noninvasive Detection of Cancer.- 10 Microbubble Contrast Agents for Molecular Ultrasound Imaging of Tumor Vasculature.- 11 Optical and Optoacoustic Imaging Probes.- 12 Artificial Intelligence and Radiomics in Molecular Oncology Imaging.- Part 2: Preclinical Studies 13 Pre-Clinical SPECT and SPECT-CT in Oncology.- 14 Preclinical Applications of Magnetic Resonance Imaging in Oncology.- 15 Optical and photoacoustic imaging.- 16 Preclinical PET, PET/CT and PET/MRI.- 17 Molecular Ultrasound Imaging.- 18 Advanced Microscopy Techniques.- Part 3: Clinical Applications 19 Quantitative SPECT/CT - Technique and Clinical Applications.- 20 Fluorescence Imaging of Cancer.- 21 FDG PET Hybrid Imaging.- 22 Non-FDG PET/CT.- 23 Clinical MR biomarkers.- 24 Potential clinical applications of hyperpolarized 13C and 2H MRI.- 25 Clinical PET/MR.- 26 Clinical Applications of Advanced Ultrasound Imaging.- 27 Image-Guided Radiooncology: The Potential of Artificial Intelligence in Clinical Application.- 28 Non-invasive Imaging Techniques: From Histology to In Vivo Imaging.- 29 Image-guided brain tumor surgery.- 30 Imaging Immunotherapy.- 31 Advancements in Intraoperative Imaging for Enhanced Surgical Precision.- Part 4: Image Guided Radiooncology 32 Molecular Imaging in Photon Radiotherapy.- 33 The Role of Molecular Imaging in Ion Beam Therapy.- 34 Internal Radiation Therapy.- 35 Clinical Applications of Theranostics.- Part 5: Future Challenges 36 Future Challenges of Molecular Imaging in Oncology.
