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Full Description
Thanks to blockbuster movies about superheroes and cloned dinosaurs, DNA now is an icon in popular culture. Yet if asked who discovered DNA, most people - including most scientists - would probably think of Watson and Crick, unaware that it all began almost a century earlier.
This book tells the story of Swiss scientist Friedrich Miescher, whose pioneering work led to the discovery of DNA. Drawing on Miescher's publications and letters, the authors trace his breakthrough - from washing pus off discarded bandages in Tübingen's medieval castle to fishing salmon in the Rhine at dawn to study their sperm - and follow how his insights were received against a backdrop of intellectual rivalries, clashing egos, and fierce feuds that raged between disciplines.
The book then explores what became of Miescher's discovery after his death, showing how a molecule long dismissed as biologically insignificant became central to powerful technologies that now shape our future. Finally, the authors examine the ethical, social, and political questions raised by such developments and why Miescher's story may matter today more than ever.
Written in an engaging and accessible style, this account of Miescher's groundbreaking work will captivate anyone interested in the discovery of one of biology's most important and enigmatic molecules.
Contents
Introduction.- 1. 'The Quiet in the Land'.- 2. Lifting the Veil.- 3. Blood Feud.- 4. The Sperm Campaign.- 5. The Great Unwashed.- 6. Hacking the Heads off the Hydra.- 7. 'The Wooden Stretcher Behind the Rembrandt'?.- 8. 'The Grammar of Biology'.- 9. 'What is Life?'.- 10. Opening the Book of Life.- 11. Breaking the Glass.- 12. The Struggle of Sisyphus.- Epilogue.- List of Figures.- Further Reading.- Bibliography.
