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Full Description
Engineers have played an important and often underrecognized role in advances in the treatment and management of sickle cell disease and in recent curative breakthroughs. This comprehensive and cutting-edge edited volume brings together renowned experts to shed light on the development and application of engineering technologies to unravel the complexities of sickle cell disease in pursuit of improved health outcomes.
This volume is intended for researchers, engineers, scientists, clinicians, and students working in the fields of engineering, genetics, hematology and other related disciplines. Medical professionals seeking to stay abreast of the most recent technological breakthroughs in sickle cell disease treatments and cures will also find this book informative. Additionally, counselors, policy makers, healthcare administrators and anyone seeking to understand the impact of engineering solutions on advances in sickle cell disease, will be intrigued by the innovations, applications and future prospects shared in this important addition to sickle cell resources.
Contents
Quantitative engineering approaches to understand the multiscale biophysical biomechanical and rheological pathophysiology of sickle cell disease.- Decoding Sickle Cell Hemorheology with Supercomputing and AI.- In vitro approaches for the investigation of blood cell endothelial cell interactions in sickle cell disease.- Bioengineering Approaches to Understanding Sickle Cell Disease Large Artery Damage Hemodynamics and Inflammation.- Measuring Biophysical Properties of Single Red Blood Cells as Potential Biomarkers of Sickle Cell Disease.- Advancing Sickle Cell Disease Management Traditional Diagnostics to Comprehensive Red Blood Cell Health.- Development and proposed use of red cell function testing in SCD.- Gene editing based approaches for curing sickle cell disease.- Therapeutic Genome Engineering for the treatment of sickle cell disease.- Hemoglobin A Target for Sickle Cell Disease Drug Discove.



