Dengue Virus Evolution: From Emergence to a Global Health Crisis : Insights into Genomics, Ecology and Epidemiology (Current Topics in Microbiology and Immunology)

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Dengue Virus Evolution: From Emergence to a Global Health Crisis : Insights into Genomics, Ecology and Epidemiology (Current Topics in Microbiology and Immunology)

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  • 製本 Hardcover:ハードカバー版/ページ数 380 p.
  • 言語 ENG
  • 商品コード 9783032099808

Full Description

This volume explores dengue's path from viral emergence to a global health crisis, providing a comprehensive examination of one of the world's most resilient and adaptable arboviruses. The individual chapters, written by leading experts in the field of dengue research, encompass multidisciplinary perspectives and illuminate the intricate dance between the dengue virus, its hosts and its environment. The viral biology and the molecular mechanisms of pathogenesis, its evolution and clinical manifestations are presented in detail. In addition, the volume offers insights into the response of the host immune system to the virus and discusses diagnostics, new vaccines and treatment strategies. In a unique way, the volume explores the link between climate change and the dynamics of virus transmission and shows groundbreaking surveillance methods that help with real-time tracking and prediction of potential outbreaks.
 
This book is aimed at researchers, advanced students and healthcare professionals in academia, industry and public authorities.

Contents

Dengue: Historical Aspects.- Tracing Dengue's Evolutionary and Phylogenetic Pathways. Cellular Biology - Virus host cells interaction - RNA structure and function.- Cellular Biology: Virus-Host Interactions and RNA Structure and Function.- Immune Response.- Innate Immune and Inflammatory  Responses to Dengue Virus Infection.- T Cell Responses During Dengue Infection.- Dengue Dilemma: Navigating Cross-Reactivity and Immune Challenges.- Diagnostic Techniques for Dengue Virus.- Vector Surveillance: A Crucial Front in Dengue Prevention.- Entomological Surveillance and Vector Competence: A Crucial Front in Dengue Prevention.- Dengue Vaccines.- Antiviral Strategies Against Dengue Virus: Recent Insights into Compounds Targeting Viral and Host Factors.- The Links Between Dengue Virus, Climate and Climate Change.- Global Genomic Surveillance: On-The-Ground Responses.- Horizons of the Future: Preparedness and Response.

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