Full Description
The book presents the currently available clinical, epidemiological, and experimental data on short bowel syndrome (SBS), with special emphasis on the medical, surgical, and nutritional care of patients affected by SBS, based on the most up-to-date, evidence-based data available.
The prevalence of SBS has been rising along with significant advances in medicine and the overcoming of barriers such as more aggressive cancer resections and the increase in life expectancy, which has led to a higher prevalence of mesenteric ischemia and thrombosis. More recently, the SARS-CoV-2 infection has caused an increase in the incidence of thrombosis. The rising prevalence of SBS has prompted researchers and healthcare professionals to explore innovative treatments such as intestinal transplantation and the development of specialized diets and medications to improve patients' quality of life.
The volume emphasizes the use of growth factors, which are likely to become increasingly important for promoting the structural adaptability of the intestine. It also highlights the need for ongoing research in the field of SBS to further understand the underlying mechanisms and develop new treatment options. Additionally, it highlights the importance of patient education and empowerment in managing their condition and making informed decisions about their care.
The importance of a skilled interdisciplinary team in providing care for these individuals is also outlined. This book will serve as a quick reference on the medical, surgical, and nutritional care of complex patients with SBS, for nutritionists, dietitians, general practitioners, gastroenterologists, surgeons, nurses, and pharmacists alike.
Contents
Chapter 1: Definition and classification of short bowel syndrome.- Chapter 2: Epidemiology and survival of short bowel syndrome.- Chapter 3: Pathophysiology and anatomical considerations in short bowel syndrome.- Chapter 4: Humanistic burden of short bowel syndrome.- Chapter 5: Intestinal adaptation - mechanisms and therapy goals.- Chapter 6: Free water, electrolytes, and acid-base balance disturbances in short bowel syndrome.- Chapter 7: Refeeding syndrome: prevention, diagnosis, and treatment.- Chapter 8: Cholelithiasis and nephrolithiasis in short bowel syndrome.- Chapter 9: D-lactate encephalopathy in patients with short bowel syndrome.- Chapter 10: Metabolic bone disease in short bowel syndrome - diagnosis and management.- Chapter 11: Intestinal failure-associated liver disease.- Chapter 12: Insights into nutritional management of short bowel syndrome - nutritional assessment and diet considerations.- Chapter 13: Home parenteral nutrition in long-term intestinal failure.- Chapter 14: Long-term venous access for HPN: types, devices, and complications.- Chapter 15: Monitoring and management of trace elements in short bowel syndrome.- Chapter 16: Enteral feeding and parenteral nutrition in short bowel syndrome - current recommendations and unmet needs.- Chapter 17: Drug pharmacokinetics and pharmacodynamics in short bowel syndrome - special considerations - Liliana Mirea Chapter 18: Antisecretory, antimotility and luminally active agents in the management of short bowel syndrome.- Chapter 19: Growth-stimulating effects of glucagon-like peptide-2, growth hormone and other agents.- Chapter 20: Surgical management of short bowel syndrome - ostomy, fistula, autologous gastrointestinal reconstruction.- Chapter 21: Intestinal transplantation in short bowel syndrome.- Chapter 22: Multidisciplinary approach in short bowel syndrome.- Chapter 23: Education of patients with short bowel syndrome.- Chapter 24: Future perspectives in short bowel syndrome - organoid-based tissue-engineered small intestine and SIC, xenotransplantation.
