Description
This title represents the definitive reference for all aspects of the skin microbiome. It represents a thorough review of the mechanical and physical mechanisms of the skin, covering the immune response to potential skin breaches and detailing the vast number of microbial challenges that the skin must repel.
The Skin Microbiome Manual explains every aspect of the protection provided by the skin, describing how it occasionally fails and how this helps in understanding the mechanisms involved. The world-class Editorial Board and their chapter authors also investigate the ways in which dermatology provides methods to prevent or overcome the deleterious effects of these challenges to the skin's integrity. This book therefore represents an essential text for all clinical dermatologists and those in training who are seeking a deeper discussion of the skin as a complex biome and how this affects dermatological health.
1. Effect of cream application in childhood on skin barrier and development of atopic disease.- 2. The human skin microbiome.- 3. Tools to explore human skin microbiota.- 4. Skin microbiota: host interactions in health and disease.- 5. Biodiversity hypothesis: role of the human microbiota in health and disease.- 6. Microbiome in patients this atopic dermatitis.- 7. Skin microbiome in psoriasis.- 8. Host-microbe interactions and the biology of acne vulgaris.- 9. Skin exploitation by viruses.- 10. Skin-dwelling fungus role in health and disease.- 11. Skin microbiome: potential for novel diagnostic and therapeutic approaches.- 12. Microbiome of skin: an overview.
Antti Lauerma is Professor of Dermatology and Allergology at University of Helsinki and Director of Inflammation Center at Helsinki University Hospital. He is an internationally recognized scientist, whose research for the last 40 years has concentrated on skin allergy, development of skin testing, prevention of allergy, as well as the role of inflammatory pathways and microbiome in chronic skin diseases. He has been in leadership positions in scientific societies such as European Society of Contact Dermatitis, European Society for Dermatological Research, European Academy of Allergology and Clinical Immunology and European Academy of Dermatology and Venereology. He is currently chair of Finnish Allergy Research Foundation and Auditor of Nordic Dermatology Association.
Nanna Fyhrquist is a Researcher at the University of Helsinki. Her research has previously focused on T cell mediated skin inflammation, and in particular on how CD4+ and CD8+ T cells contribute to contact hypersensitivity (CHS) responses and on the role of T regulatory cells in experimental atopic dermatitis. Currently she is leading a project which aims at identifying biomarkers discriminating between human irritant and allergic contact dermatitis, and involved in multiple projects which explore host-microbe interplay in health and allergic disease and autoimmunity.
Howard I. Maibach is one of the leading US-American dermatologists. He has written and lectured extensively on dermatotoxicology (the toxicity to man from skin exposure) and dermatopharmacology (the treatment of skin diseases). Dr. Maibach has been on the editorial boards of over 30 scientific journals and is a member of 19 professional societies. When seeing patients he mostly provides second opinions on allergic contact dermatitis.
Bernhard Homey is the Director of the Dept. of Dermatology at the University Hospital Düsseldorf. He is an internationally recognized clinician scientist and immunologist focusing on the underlying mechanisms of chronic inflammatory and autoimmune skin diseases. His research is centered around the biology of cytokines and chemokines, neuroimmune pathways as well as microbe-host interactions. The integration of multi-OMICs datasets including metagenomics and the development of novel therapeutic strategies are current interests.
