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Full Description
When our food items become contaminated with pathogenic microorganisms, these microorganisms secrete microbial toxins which promote infection by attacking the host tissue's immune system, thereby leading to foodborne intoxication, or poisoning, in consumers. Because these toxic microorganisms are not typically identifiable by taste, smell or sight, it is crucial to the safety of our food systems that they be detected through microbial testing.
As the title suggests, Microbial Toxins: Causes, Mechanisms, Complications and Metabolism is a comprehensive overview of the life of these toxins from their pathogenesis through to their implications for human and environmental health. Including examples of salmonella, botulism, listeria and more, as well as various mycotoxins, this text will appeal to both microbiology researchers as well as food industry professionals. Beyond foodborne illness, this text also unpacks environmental toxicology and the role of microbial toxins in the development of novel anti-cancer drugs.
Emerging techniques in the detection of microbial toxins will be discussed, setting this text apart from existing books on the subject. The use of proteomics in toxin identification, for example, allows for the determination of metabolic pathways and biomarkers of pathogenicity and resistance of biotoxins. This text furthers the study of foodborne hazards and has important implications for the improvement of safety in the food industry.
Contents
Introduction: Concept, Significance and Properties of Microbial Toxins.- Toxicological Terms.- Pathogenicity Mechanisms of Bacteria.- Beneficial roles of microbial toxins.- Detection of Bacterial Toxins.- Microbial toxins degradation.- Environmental toxicology.- Bacterial Toxins: Genetics, Cellular Biology and Practical Applications.- Food Industry and Microbiological Toxins Contamination.- Proteomics as a tool for studying of microbial toxins.- Detection and Identification of microbial toxins by Proteomics Approaches.- Food Intoxication Prevention, Diagnoses, and Treatment.- Significance of bacterial toxins.- Bacterial protein toxins.- Bacterial Toxins and Human Health.- Bacterial Toxins and cancer.- Endotoxins and external bacterial toxins.- New discoveries in toxins from Gram-positive bacteria, Staphylococcus aureus.- New discoveries in toxins from Gram positive bacteria, Clostridium botulinum.- New discoveries in toxins from Gram negative bacteria Eschrichia coli.- New discoveries in toxins from Gram negative bacteria Salmonella.- New discoveries in toxins from Gram negative bacteria Vibrio Cholerae.- New discoveries in toxins from Gram-positive bacteria, Listeria monocytogenes.- New discoveries in toxins from Campylobacter.- Mycotoxins, producing fungi, types and properties.- Aflatoxins Occurrence, Toxicity Effects and Degradation.- Ochratoxins Toxins.- Zearalenone Toxins.- Mushroom poisons.- Patulin Toxins.- Citrulline Toxins.- Algal toxins.- Viral Toxins.- Implications of Mycotoxins in Food Safety and Regulations.- Bacterial toxins in the management of colon cancer Current perspective.
