Full Description
Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.
Contents
Section I: General Considerations.- Chapter 1: Pharmacogenetics of Cutaneous Adverse Drug Reactions.- Chapter 2: Mechanisms of Drug Hypersensitivity.- Chapter 3: Histopathology of Cutaneous Adverse Drug Reactions.- Chapter 4: Skin Tests in Evaluating Drug Eruptions.- Chapter 5: In vitro Drug Allergy Testing.- Section II: Reaction Patterns.- Chapter 6: Drug-induced urticaria.- Chapter 7: Exanthematous Drug Eruptions.- Chapter 8: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.- Chapter 9: Acute Generalized Exanthematous Pustulosis.- Chapter 10: Drug Reaction Eosinophilia and Systemic Symptoms (DRESS).- Chapter 11: Fixed Drug Eruptions and Generalized Bullous Fixed Drug Eruptions.- Chapter 12: Lichenoid Drug Eruptions.- Chapter 13: Drug-induced Connective Tissue Disorders.- Chapter 14: Drug-induced Vasculitis.- Chapter 15: Drug-induced Autoimmune Bullous Diseases.- Chapter 16: Other Drug-induced Inflammatory Skin Reactions.- Chapter 14: Drug-induced Vasculitis.- Chapter 15: Drug-induced Autoimmune Bullous Diseases.- Chapter 16: Other Drug-induced Inflammatory Skin Reactions.- Chapter 17: Drug-induced Photosensitivity.- Chapter 18: Drug-induced Pruritus Without Primary Rash.- Chapter 19: Drug-induced Nail Changes.- Chapter 20: Drug-induced Hair Changes.- Chapter 21: Drug-induced Pigmentary Disorders.- Section III: Special Drug Categories.- Chapter 22: Immediate and Delayed Reactions to Beta-lactams.- Chapter 23: Hypersensitivity Reactions to Iodinated Radiocontrast Media.- Chapter 24: Cutaneous Adverse Reactions to Biologic Agents.- Chapter 25: Cutaneous Reactions to Oncologic Targeted Therapy.- Chapter 26 :Cutaneous Reactions to Oncologic Immunotherapy.
