Full Description
This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.
Contents
Epidemiology and Cancer Prevention.- Tumor biology and natural history.- Histopathology of the Tumors.- Biomarkers.- Liquid biopsy.- Diagnosis and staging.- Molecular Diagnostics: innovative technologies for clinical and translational research.- Hereditary cancers and genetics.- Principles of anti-cancer therapy: Chemotherapy.- Principles of anti-cancer therapy: Hormonal therapy.- Principles of anti-cancer therapy: Target Therapy.- Principles of anti-cancer therapy: Immunotherapy.- The role of Surgery.- Surgery in the Management of Gastrointestinal Stromal Tumors.- Integrated Treatments: The role of radiotherapy.- Response assessment to cancer therapy.- Clinical trials and methodology in cancer research.- Basic principles of bioinformatics for next generation sequencing molecular testing in oncology.- New drugs development.- Treatment toxicity.- Cardioncology.- The cancer cachexia.- Support and palliative care.- Physician-Patient Communication.- Breast Cancer: Locoregional and locally advanced disease.- Metastatic breast cancer.- Chest Tumors: Lung Cancer.- Malignant Pleural Mesothelioma.- Gastrointestinal Cancers: Oesophagus.- Gastric cancer.- Gastrointestinal Cancers: Stomach, advanced/metastatic disease.- Gastrointestinal Cancers: Colorectum, locoregional disease.- Metastatic colorectal cancer.- Anal Carcinoma.- Gastrointestinal Cancers: exocrine pancreas.- Gastrointestinal Cancers - Biliary cancer.- Hepatocellular Carcinoma.- Head and Neck Cancers (HNCs).- Central Nervous System Malignancies.- Genitourinary cancers: Kidney.- Bladder Cancer.- Genitourinary cancers: Prostate, locoregional disease.- Advanced and Metastatic Prostate Cancer.- Genitourinary cancers: Testis.- Genitourinary cancers: Penis.- Gynaecological cancers: Ovaris, early primary disease.- Gynaecological cancers: Ovaris, primary advanced and recurrent disease.- Gynaecological cancers: Uterus, endometrial and cervical cancer.- Vulvar and Vaginal Cancer.- Endocrine cancers: Adrenal gland.- Endocrine cancers: Thyroid.- Neuroendocrine Tumors.- Cutaneous Melanoma and other skin cancers.- Soft Tissue Sarcomas (STS).- The Role of Medical Treatment in the management of Gastrointestinal Stromal Tumors (GIST).- Bone health in cancer patients.- Nutrition and cancer.- Personalized medicine.- Categorization of Cancer Survivors.- Precision medicine in oncology: glossary of relevant scientific terms.
