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Full Description
This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy.
With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and "lifestyles" of fungi. The second section, Biotechnology, addresses theapplied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.
Contents
Chromatin Structure and Function in Neurospora crassa.- Origin, function and transmission of accessory chromosomes.- Genetics of the unfolded protein response in fungi.- From genetics to molecular oscillations: the circadian clock in Neurospora crassa.- small RNAs in fungi.- NLR function in fungi as revealed by the study of self/non-self recognition systems.- Genetics and genomics decipher partner biology in arbuscular mycorrhizas.- Coordination of fungal secondary metabolism and development.- Fungal Genomics.- Filamentous fungi as hosts for heterologous production of proteins and secondary metabolites in the post-genomic era.- New Avenues towards drug discovery in fungi.- Exploiting fungal photobiology as a source of novel bio-blocks for optogenetic systems.- Yeast cell factories.- Engineering Saccharomyces cerevisiae for production of fatty acids and their derivatives.- Fungi Involved in the Biodeterioration and Bioconversion of Lignocellulose Substrates.- Biotechnology of marine fungi: New workhorses and new uses - using marine fungal diversity as a source for biotechnology.- The biotechnological potential of anaerobic gut fungi.
