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Full Description
Nanotechnology in Pharmaceutical Aerosol Science and Pulmonary Delivery presents a comprehensive reference dedicated to the intersection of nanotechnology and inhalation drug delivery. Edited by internationally recognized experts Professors Heidi M. Mansour and Anthony J. Hickey, this authoritative volume explores the design, development, and evaluation of inhaled nanomedicines for targeted pulmonary therapy.
Bringing together contributions from leading researchers across academia, industry, and regulatory sectors, the book covers a wide spectrum of topics—from the physicochemical properties of nanomaterials and formulation strategies, to advanced in vitro and in vivo models, biopharmaceutical classification, and regulatory perspectives. Chapters delve into cutting-edge applications including nanoliposomes, nanocrystals, dendrimers, exosomes, and inhaled biologics, with a strong emphasis on translational science and therapeutic innovation.
It serves as an essential resource for pharmaceutical scientists, nanotechnologists, biomedical scientists, clinicians, industrial scientists, and regulatory professionals. In addition, it serves as a valuable scientific resource for educators and students.
Contents
Introduction
Nanomaterials Used in Inhaled Pulmonary Delivery Systems
Inhaled Nanoliposomes for Treating Lung Disease Including a Case Study of Amikacin Liposome Inhalation Suspension (ALIS)
Natural Killer Cells-derived Exosomes as Delivery Systems for Overcoming Resistance in NSCLC
Inhaled Formulations of mRNA - Lipid Nanoparticles (LNPs): Barriers and Formulation Strategies
Nanocharacterization of Pharmaceutical Inhalable Particles
Multi-stage Cascade Impactors: Their Use and Limitations for the Development and Commercialization of Inhaled Pharmaceuticals Containing Formulations Based on Nanotechnology
Dissolution Testing for Inhaled Nanoparticlulate Drug Delivery Systems
Pulmonary Surfactants and Pulmonary Drug Design and Delivery
Harnessing Inhaled Nanoparticles for Enhanced Pharmacokinetics and Pharmacodynamics of Drugs
Interactions of Nanoparticles with Structures of the Respiratory System, Nanoparticle Endocytosis by Cells and Cell Responses
Polymeric Nanoparticles Targeting Lung Innate Immune Cells
Inhalable Nanoparticles for Lung Immunotherapy
General Conclusion
