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Full Description
This collection features four peer-reviewed literature reviews on developing immunity in pigs.
The first chapter provides an overview of the latest research in gut function and immunity in pigs, as well as the role of the gut microbiota in shaping intestinal immune responses. The chapter also reviews recent advances in the development of novel tools to investigate the function of the pig gut.
The second chapter describes the enteric and mucosal immune systems of pigs and presents evidence from experimental studies of the links between the immune system and microbiota. It examines the microbiome and metabolism of pigs and highlights its importance in the development of pig immune systems.
The third chapter reviews advances in nutritional strategies to boost immune function in pigs, including the use of lipopolysaccharide to stimulate the immune system. The chapter considers the need to reduce the use of antimicrobials in swine diets and reviews the effect of dietary supplementation during key stages of a pig's life to enhance immunity.
The final chapter assesses methods of improving gut function in pigs to optimise health, prevent pathogen colonization and optimise immunity. The chapter discusses research on genes associated with pathogen resistance and porcine immune response and reviews the role of dietary and nutritional strategies in preventing intestinal pathogen colonisation.
Contents
Chapter 1 - Advances in understanding gut function and immunity in pigs: Bert Devriendt, Ghent University, Belgium; 1 Introduction2 Architecture of the intestine3 The intestinal epithelium control of gut immunity4 The Gut-Associated Lymphoid Tissues5 The role of the gut microbiota in shaping gut function and immunity6 Intestinal organoids as novel tools to explore the function of the gut7 Conclusions and outlook8 References
Chapter 2 - The influence of gut microbiome on developing immune and metabolic systems in the young pig: Mick Bailey, Emily Porter and Ore Francis, University of Bristol, UK; 1 Introduction2 The mucosal immune system3 Experimental studies of the links between the immune system and microbiota4 The microbiome and metabolism5 Conclusion6 Where to look for further information7 References
Chapter 3 - Nutritional strategies to boost immune function in pigs: Glen W. Almond, North Carolina State University, Raleigh, NC, USA and Sara D. Hough, DSM Nutritional Products, Parsippany, NJ, USA; 1 Introduction2 How does immune challenge affect pig growth?3 Pregnancy, lactation and pre-weaned piglets4 Proteins and amino acids5 Lipids and fatty acids6 Glucans and carbohydrates7 Minerals8 Vitamins9 Nonnutritive feed additives10 Summary and future directions11 Where to find additional information12 References
Chapter 4 - Improving gut function in pigs to prevent pathogen colonization: P. Bosi, D. Luise and P. Trevisi, University of Bologna, Italy; 1 Introduction2 The main gut-related pathogens in pigs3 Pig genetics and resistance to disease4 Management strategies affecting gut functionality and pathogen colonization5 Dietary strategies to improve gut functionality and prevent pathogen colonization: feed size6 Dietary strategies to improve gut functionality and prevent pathogen colonization: protein and dietary fibre7 Dietary strategies to improve gut functionality and prevent pathogen colonization: dietary nitrate, organic and amino acids8 Dietary interventions for pathogen-specific defence9 Future trends and conclusion10 Where to look for further information11 References
