人工知能による化学エキスパート・システム(第2版)<br>Knowledge-based Expert Systems in Chemistry : Artificial Intelligence in Decision Making (2ND)

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人工知能による化学エキスパート・システム(第2版)
Knowledge-based Expert Systems in Chemistry : Artificial Intelligence in Decision Making (2ND)

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  • 製本 Hardcover:ハードカバー版/ページ数 284 p.
  • 言語 ENG
  • 商品コード 9781788014717
  • DDC分類 542.85633

Full Description

There have been significant developments in the use of knowledge-based expert systems in chemistry since the first edition of this book was published in 2009. This new edition has been thoroughly revised and updated to reflect the advances.

The underlying theme of the book is still the need for computer systems that work with uncertain or qualitative data to support decision-making based on reasoned judgements. With the continuing evolution of regulations for the assessment of chemical hazards, and changes in thinking about how scientific decisions should be made, that need is ever greater. Knowledge-based expert systems are well established in chemistry, especially in relation to toxicology, and they are used routinely to support regulatory submissions. The effectiveness and continued acceptance of computer prediction depends on our ability to assess the trustworthiness of predictions and the validity of the models on which they are based.

Written by a pioneer in the field, this book provides an essential reference for anyone interested in the uses of artificial intelligence for decision making in chemistry.

Contents

Artificial Intelligence - Making Use of Reasoning;

Synthesis Planning by Computer;Other Programs to Support Chemical Synthesis Planning;

International Repercussions of the Harvard LHASA Project;

Current Interest in Synthesis Planning by Computer;

Structure Representation;

Structure, Substructure and Superstructure Searching;

Protons That Come and Go;

Aromaticity and Stereochemistry;

DEREK - Predicting Toxicity;

Other Alert-based Toxicity Prediction Systems;

Rule Discovery;

The 2D-3D Debate;

Making Use of Reasoning: Derek for Windows;

Predicting Metabolism;

Relative Reasoning;

Predicting Biodegradation;

Other Applications and Potential Applications of Knowledge-based Prediction in Chemistry;

Combining Predictions;

The Adverse Outcome Pathways Approach;

Evaluation of Knowledge-based Systems;

Validation of Computer Predictions;

Artificial Intelligence Developments in Other Fields;

A Subjective View of the Future

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