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Full Description
Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph primarily covers the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book provides a reference for researchers working in different fields, creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context, provides a One Health approach to these important groups of diseases.
Contents
Introduction: The Many Hosts of Mycobacteria: An Interdisciplinary Approach to Understanding Mycobacterial Diseases Part I: Tuberculosis in Humans 1: Introduction and Epidemiology of Mycobacterium tuberculosis Complex in Humans 2: Comparative Mycobacteriology of the Mycobacterium tuberculosis Complex 3: Immunopathogenesis of Tuberculosis in Humans 4: Current Methods for Diagnosis of Human Tuberculosis and Considerations for Global Surveillance 5: Development of Next-generation TB Vaccines: Comparative Approaches in Humans and Animals 6: The Continuing Co-evolution of Mycobacterium tuberculosis and Homo sapiens Part II: Tuberculosis in Domesticated and Companion Animal Species 7: The Global Distribution of Mycobacterium bovis 8: Immunopathogenesis of Mycobacterium bovis Infection of Cattle 9: Diagnosis of Mycobacterium bovis Infection in Cattle 10: Vaccination of Cattle Against Tuberculosis 11: Mycobacterium bovis/M. caprae Infection in Goats and Sheep: Introduction, Epidemiology and Control Measures 12: Mycobacterial Infections in Camelids 13: Tuberculosis in Companion Animal Species Part III: Mycobacterial Infections in Zoo Species 14: Mycobacterial Infections in Elephants 15: Mycobacterial Infections in Other Zoo Animals Part IV: Tuberculosis in Wildlife 16: Tuberculosis in Badgers (Meles meles) 17: Tuberculosis in Pigs and Wild Boar 18: Australian Brushtail Possum: A Highly Susceptible Host for Mycobacterium bovis 19: Tuberculosis in Wild and Captive Deer 20: Tuberculosis in South African Wildlife: Lions, African Buffalo and Other Species 21: Novel Mycobacterium tuberculosis Complex spp. in Group-living African Mammals Part V: In Vivo Laboratory Models of Tuberculosis 22: Rabbit Model of Mycobacterial Diseases 23: Laboratory Models of Tuberculosis: Guinea Pigs 24: Of Mice and Mycobacteria: Lessons from a Manipulatable Model 25: Non-human Primate Laboratory Models of Tuberculosis Part VI: Other Mycobacterial Diseases 26: Mycobacterium leprae in Humans 27: Animal Models for Leprosy Research 28: Mycobacterium avium subsp. paratuberculosis Infection, Immunology and Pathology of Livestock 29: Nontuberculous Mycobacterial Infections
