Full Description
There has been a tremendous advancement in cancer therapeutics, and this book focuses on new approaches to one of the major cancers of the female reproductive system—cervical cancer. Cervical cancer is the fourth most frequent cancer in women worldwide and, especially, a foremost cause of morbidity in women in developing countries, including India. Several research findings have suggested that modulation in various signaling pathways is responsible for cervical cancer pathogenesis, and inhibition of these crucial pathways could be a better therapeutic approach for cervical cancer management. This book expounds on this approach, providing a detailed insight of the deregulated oncogenic signaling pathways involved in the progression of cervical cancer.
The key topics covered within this book include
Signaling pathways involved in cervical cancer
Mechanisms behind the involvement of these aberrant signaling pathways
Cell signaling pathways and their alterations in cancer
Molecular biology behind cervical cancer
Drug development approaches for the management of cervical cancer
Cervical cancer therapeutics and the possible aspects, including progression and inhibition using natural products and synthetic approaches
Oncologists, cancer scientists, and research professionals will benefit from this volume, which provides a single platform that presents new research on the pathways responsible for the progression of cervical cancer so that they, in turn, can design their research work effectively and can discover novel innovations in the field of cancer therapeutics.
Contents
Foreword by Natália Cruz-Martins, PhD, Faculty of Medicine, University of Porto, Portugal 1. Cervical Cancer: Global Incidences and Progression 2. Wnt Signalling Pathway in Cervical Cancer 3. TLR Signalling Pathway in Cervical Cancer 4. PI3K-Akt-Mtor Signalling Pathways 5. Notch Signalling Pathway 6. Apoptotic Pathways in Cervical Cancer Management 7. NF-Kb in Cervical Cancer Management 8. JAK-STAT Pathway in Cervical Cancer Management 9. Role of Micro-RNA in Cervical Cancer Progression and Its Therapeutic Implications 10. Cervical Cancer and Natural Products: Anticancer Potential and Mode of Action 11. Therapeutic Approaches for Cervical Cancer Management
