Full Description
Cardiovascular disease has evolved into an epidemic health concern. During the past decades, considerable effort has been made to develop novel and safer therapeutic options. Gene therapy has offered much renewed hope and instigated the present book. For the treatment of cardiovascular disease gene therapy has risen to an interesting and important point of view of curing disease. Although most of the studies are still experimental beneath a well defined number of clinical studies, more and more studies are designed to be carried out in humans. Based on a rich compilation of scientific as well as clinical studies around the world, this book gives insights into the general principles of gene transfer as well as therapeutic strategies including stem cell therapy as an alternative approach to gene therapy.
Contents
Preface; Introduction; General principles of gene transfer; Gene delivery techniques; Gene therapy for coronary atherosclerosis & myocardial ischemia; Gene therapy for heart failure; Gene therapy for myocardial inflammation/myocarditis; Gene therapy for atrial arrhythmia; Gene therapy for ventricular arrhythmia; Stem cell therapy for cardiovascular disease; Gene transfer as biological pacemakers; Gene therapy clinical trials; Summary & conclusion; Index.NER(01): GB IE