Microbial Genomes (Infectious Disease)

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Microbial Genomes (Infectious Disease)

Fraser, Claire M. (EDT)/ Read, Timothy (EDT)/ Nelson, Karen E., Ph.D.

ウェブストア価格 ¥44,602（本体¥40,548）
Springer（2010/10発売）
外貨定価 US$ 219.99
ポイント 405pt

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製本 Paperback:紙装版/ペーパーバック版／ページ数 552 p.
言語 ENG
商品コード 9781617374111
DDC分類 579

Full Description

This collection of diverse articles by the pioneers of modern genomics takes stock of the current state of the field and elucidates the contribution that sequencing genomes has made to our understanding of microbial metabolism and evolution. Through twenty-eight thought-provoking chapters, the authors describe some of the most common computational methods and their applications to studying pathogenic microorganisms, show how genomics can be used to reconstruct the history and dynamism of the microbial world, and discuss issues as diverse as reconstruction of metabolic pathways, cell cycle processes, microbial evolution, metagenomics, and vaccine development. Additional chapters deal with microarrays and expression analysis and the role of genomic in drug discovery.

Part I: Introduction

History of Microbial Genomics
Hamilton O. Smith

Part II: Bioinformatics As a Tool in Genomics

Tools for Gene Finding and Whole Genome Comparison
Steven L. Salzberg and Arthur L. Delcher

Bacterial Genome Annotation at TIGR
Owen White

Bioinformatics and Microbial Pathogenesis
Fiona S. L. Brinkman and Joanna L. Fueyo

Bacteriophage Bioinformatics
Derrick E. Fouts

Part III: Core Functions

Comparative Microbial Metabolism
Karen E. Nelson

Genomic Analysis of Membrane Transport
Ian T. Paulsen, Katherine H. Kang, Mark E. Hance, and Qinghu Ren

Genomics-Based Analysis of the Bacterial Cell Cycle
Michael T. Laub, Harley H. McAdams, and Lucy Shapiro

Part IV: The Evolution of Microbial Genomes

A Brief History of Views of Prokaryotic Evolution and Taxonomy
Lorraine Olendzenski, Olga Zhaxybayeva, and J. Peter Gogarten

How Bacterial Genomes Change
Timothy D. Read and Garry S. A. Myers

Concepts of Bacterial Biodiversity for the Age of Genomics
Frederick M. Cohan

Coevolution of Symbionts and Pathogens With Their Hosts
Robert A. Feldman

Part V: A Survey of Microbial Genome

A Survey of Plant Pathogen Genomes
C. Robin Buell

Anoxygenic Phototrophic Bacteria
F. Robert Tabita and Thomas E. Hanson

Genomics of Thermophiles
Frank T. Robb

The Genomes of Pathogenic Enterobacteria
Julian Parkhill and Nicholas R. Thomson

Obligate Intracellular Pathogens
Siv G. E. Andersson

Low G+C Gram-Positive Genomes
Steven R. Gill

Genomics of Actinobacteria, the High G+C Gram-Positive Bacteria
Stephen D. Bentley, Roland Brosch, Stephen V. Gordon, David A. Hopwood, and Stewart T. Cole

Parasite Genomics
Malcolm J. Gardner

Genome Sequence of an Extremely Halophilic Archaeon
Shiladitya DasSarma

Part VI: Applications of Genomic Data

Microarrays, Expression Analysis, and Bacterial Genomes
Carsten Rosenow and Brian Tjaden

Microbial Population Genomics and Ecology: A New Frontier
Edward F. Delong

Application of Genomics to Biocatalysis and Biodegradation
Lawrence P. Wackett

Enzyme Discovery and Microbial Genomics
Robert M. Kelly and Keith R. Shockley

Integration of Genomics in the Drug Discovery Process
Jacques Ravel

A Genomic Approach to Vaccine Development
Rino Rappuoli, Vega Masignani, Mariagrazia Pizza, Guido Grandi, and John L. Telford

Microbial Proteomics
Svend Birkelund, Brian B. Vandahl, Allan C. Shaw, and Gunna Christiansen

Index