Full Description
A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.
Contents
Signs and Symptoms of Multiple Sclerosis.- Differential Diagnosis, Clinical Features, and Prognosis of Multiple Sclerosis.- Role of Magnetic Resonance Imaging in the Diagnosis and Prognosis of Multiple Sclerosis.- Cognitive Dysfunction in Multiple Sclerosis.- Multiple Sclerosis, Genetics, and Autoimmunity.- B-Cell Immunity in Multiple Sclerosis.- Multiple Sclerosis.- Pregnancy and Multiple Sclerosis.- Treatment of Progressive Multiple Sclerosis.- Cyclophosphamide Therapy for Multiple Sclerosis.- Repair and Neuroprotective Strategies in Multiple Sclerosis.- Future Therapies for Multiple Sclerosis.
