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基本説明
Bringing together foremost experts, this book reviews groundbreaking gene-environment research and explores implications for clinical practice, prevention, and public policy.
Full Description
Bringing together foremost experts, this book reviews groundbreaking gene-environment research and explores implications for clinical practice, prevention, and public policy. Presented is cutting-edge work on the interplay of genetic factors and childhood experiences in the development of mental disorders such as depression, conduct disorder, and schizophrenia. Essential topics include what scientists currently know about ""susceptibility genes""; the mechanisms by which maltreatment and other stressors interact with biological susceptibilities across development; and factors that make certain children more resilient than others. Future directions for personalizing treatment and prevention efforts, thus making them more effective, are discussed.
Contents
I. Scientific Understanding1. Gene-Environment InterplayIssues and Challenges, Michael Rutter2. Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits, Avshalom Caspi, Ahmad R. Hariri, Andrew Holmes, Rudolf Uher, and Terrie E. Moffitt 3. Neurobiological Mechanisms Supporting Gene-Environment Interaction Effects, Ahmad R. Hariri4. Neurogenetic Mechanisms of Gene-Environment Interactions, Andreas Meyer-Lindenberg5. Gene-Environment Interactions: State of the Science, Michael Rutter and Kenneth A. DodgeII. Practice and Policy6. Marital Dynamics and Child Proaction: Genetics Takes a Second Look at Developmental Theory, David Reiss and Jenae M. Neiderhiser7. Gene-Environment Interactions for Delinquency: Promises and Difficulties, Guang Guo8. Genes, Environment, and Personalized Treatment for Depression, Rudolf Uher9. Promoting Resilience in Maltreated Children, Joan Kaufman and Francheska Perpletchikova10. Shaping Society through Social Policy: Will the Gene-Environment Revolution Make a Difference?, E. Jane Costello11. Gene-Environment Interactions, Criminal Responsibility, and Sentencing, Stephen J. Morse12. Gene-Environment Studies in the Era of Full-Genome Sequencing: Some Lessons from Eugenics and the Race-IQ Debates, Robert Cook-Deegan13. Genes, Environments, and Public Policy, Kenneth A. Dodge and Michael Rutter