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Full Description
Published by Sinauer Associates, an imprint of Oxford University Press.
An Introduction to Population Genetics is intended as a text for a one-semester biology course in population genetics at the undergraduate or graduate levels. The goal of the book is to introduce both classical population genetics theory developed in terms of allele and haplotype frequencies and modern population genetics theory developed in terms of coalescent theory. Numerous applications of theory to problems that arise in the study of human and other populations are presented. Appendices provide the mathematical background necessary to understand the basic theory.
Contents
Preface.- Introduction.- 1. Allele Frequencies, Genotype Frequencies, and Hardy-Weinberg Equilibrium.- 2. Genetic Drift and Mutation.- 3. Coalescence Theory: Relating Theory to Data.- 4. Population Subdivision.- 5. Inferring Population History and Demography.- 6. Linkage Disequilibrium and Gene Mapping.- 7. Selection I.- 8. Selection in a Finite Population.- 9. The Neutral Theory and Tests of Neutrality.- 10. Selection II: Interaction and Conflict.- 11. Quantitative Genetics.- Appendix A. Basic Probability Theory.- Appendix B. The Exponential Distribution and Coalescence Times.- Appendix C. Maximum Likelihood and Bayesian Estimation.- Appendix D. Critical Values of the Chi-square Distribution with d Degrees of Freedom.- Answers to Exercises.- Glossary.
