Full Description
Since the publication of the first book, "Psychosocial Aspects of Narcolepsy" in 1992 (Haworth Press), edited by Meeta Goswami, Michael Thorpy, et al., new data have emerged illustrating the damaging effects of narcolepsy on the quality of life of affected individuals. Moreover, since 1992, several discoveries and changes related to narcolepsy have been made, such as: new treatment modalities - i.e., Provigil, Xyrem and more recently, atomoxetine and armodafinil; the discovery of the role of the hypocretin/orexin system in narcolepsy; recent evidence lending support to the hypothesis that narcolepsy may be an autoimmune condition; new information on the genetics of narcolepsy; and, a revised definition of narcolepsy according to the International Classification of Sleep Disorders 2005. Furthermore, recent studies in the USA, Canada, Europe, and Australia document the negative effects of narcolepsy on the quality of life of those who have this disorder. In light of these new developments, and given the absence of a book that comprehensively covers the current thoughts and trends on Narcolepsy (as revealed by a review of current books on narcolepsy), this proposal is timely.
Contents
Foreword Clifford C. Saper, MD, PhD Preface Editors Credits and Acknowledgements Editors SECTION I: ETIOLOGY 1. Narcolepsy: Genetic predisposition and pathophysiology Emmanuel Mignot, MD, PhD. 2. Animal models of narcolepsy: Developments, findings, and perspectives Christopher M. Sinton, PhD. 3. Neuroimaging of narcolepsy Eric A. Nofzinger, MD. SECTION II: CLINICAL CONSIDERATIONS 4. Epidemiology of narcolepsy Lauren Hale, PhD. 5. Narcolepsy in Childhood Shalini Paruthi, MD. & Suresh Kotagal, MD. 6. Narcolepsy in the Older Adult Hrayr Attarian, MD. 7. Diurnal and nocturnal sleep in narcolepsy with cataplexy Yves Dauvilliers, MD, PhD & Giuseppe Plazzi, MD, PhD 8. Hypnagogic Hallucinations and Sleep Paralysis Armando D'Agostino, MD & Ivan Limosani, MD. 9. REM sleep behaviour disorder in narcolepsy with cataplexy. Giuseppe Plazzi, MD, PhD & Yves Dauvilliers, MD, PhD. 10. Narcolepsy and other comorbid medical illnesses Lori A. Panossian, MD & Alon Y. Avidan, MD, MPH. 11. Humor processing in human narcolepsy with cataplexy Aurelie Ponz & Sophie Schwartz, PhD. 12. Dreams in patients with narcolepsy Michael Schredl 13. Psychoanalysis and narcolepsy James F Pagel, MS, MD & Lawrence Scrima, PhD 14. Symptomatic narcolepsy or hypersomnia, with and without hypocretin (orexin) deficiency Kanbayashi T, Nakamura M, Shimizu T, & Seiji Nishino, MD, PhD. 15. Hypersomnias other than narcolepsy: Differential diagnosis Michel Billiard, MD. SECTION III: PSYCHOSOCIAL CONSIDERATIONS 16. Psychosocial impact of narcolepsy in children and adolescents Gregory Stores MA, MD, DPM, FRCPsych, FRCP. 17. Quality of life and psychosocial issues in narcolepsy Meeta Goswami BDS, MPH, PhD. 18. Narcolepsy, Intimacy and Sexuality Gila Lindsley, Ph.D. 19. Narcolepsy, driving and traffic safety Claire EHM Donjacour, Monique AJ Mets, Joris C Verster, PhD. 20. Memory and Cognition in Narcolepsy Christian Bellebaum, & Irene Daum, PhD. 21. Medico-legal aspects of disability in narcolepsy Francesca Ingravallo and Giuseppe Plazzi 22. Narcolepsy and mental health John Shneerson, MA, DM, MD, FRCP, FCCP SECTION IV: MANAGEMENT 23. Overview of management of narcolepsy Seiji Nishino, MD, PhD. 24. Modes of action of drugs related to narcolepsy: Pharmacology of wake-promoting compounds and anticataplectics Seiji Nishino, MD, PhD & Nozomu Kotorii, MD, PhD. 25. Modafinil/ Armodafinil in the Treatment of Narcolepsy Michael Thorpy, MD 26. Sodium oxybate in the treatment of narcolepsy Geert Mayer 27. Emerging treatments for narcolepsy Meredith Broderick MD & Christian Guilleminault MD, BiolD. 28. Non-pharmacologic Treatments of Narcolepsy Renee Monderer, MD, Shelby Freedman Harris, PsyD, CBSM. & Michael J. Thorpy, MD.
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