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基本説明
Helps scientists solve their biological problems by helping them understand the basics of programming.
Full Description
Programming knowledge is often necessary for finding a solution to a biological problem. Based on the author's experience working for an agricultural biotechnology company, Python for Bioinformatics helps scientists solve their biological problems by helping them understand the basics of programming. Requiring no prior knowledge of programming-related concepts, the book focuses on the easy-to-use, yet powerful, Python computer language.The book begins with a very basic introduction that teaches the principles of programming. It then introduces the Biopython package, which can be useful in solving life science problems. The next section covers sophisticated tools for bioinformatics, including relational database management systems and XML. The last part illustrates applications with source code, such as sequence manipulation, filtering vector contamination, calculating DNA melting temperature, parsing a genbank file, inferring splicing sites, and more. The appendices provide a wealth of supplementary information, including instructions for installing Python and Biopython and a Python language and style guide.By incorporating examples in biology as well as code fragments throughout, the author places a special emphasis on practice, encouraging readers to experiment with the code. He shows how to use Python and the Biopython package for building web applications, genomic annotation, data manipulation, and countless other applications.
Contents
PROGRAMMINGIntroductionFirst Steps with PythonBasic Programming: Data TypesProgramming: Flow ControlDealing with FilesCode ModularizingError HandlingIntroduction to Object Orienting Programming (OOP)Regular ExpressionsBIOPYTHONIntroduction to BiopythonADVANCED TOPICSWeb ApplicationsXMLPython and DatabasesCollaborative Development: Version ControlPYTHON RECIPES WITH COMMENTED SOURCE CODE Sequence Manipulation in BatchWeb Application for Filtering Vector ContaminationSearching for PCR Primers Using Primer3Calculating Melting Temperature from a Set of PrimersFiltering out Specific Fields from a Genbank FileConverting XML Blast File into HTMLInferring Splicing Sites DNA Mutations with Restrictions Web Server for Multiple Alignment Drawing Marker Positions Using Data Stored in a DatabaseAppendix A: Python and Biopython Installation Appendix B: Selected Papers Appendix C: Included DVD: Virtual Machine Installation and UseAppendix D: Python Language ReferenceAppendix E: Answers to Odd-Numbered QuestionsAppendix F: Python Style GuideIndex



