Full Description
Myasthenia gravis (MG), an acquired immune syndrome affecting proteins at the neuromuscular junction, causes significant muscular functional impairment and can compromise patients' quality of life, including fatigue, disability, and increased mortality rates. Continued efforts in the last decades have begun to produce significant progress in our understanding of this rare condition, yet considerable challenges remain for improving diagnosis and developing effective treatments for MG. The present volume comprises papers stemming from the "12th International Conference on Myasthenia Gravis and Related Disorders," held May 21-23, 2012 at the New York Academy of Sciences in New York City.
The papers collected in this second of two Annals volumes highlight some of the key developments in neuroscience and immunology in MG and related syndromes presented at the conference, including treatment update and what lies ahead, congenital myasthenic syndromes, Lambert-Eaton myasthenic syndrome, the thymus, thymectomy, and the myasthenia gravis thymectomy trial, and hot topics selected from submitted abstracts.
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Contents
Neuromuscular Junction Physiology and Pathophysiology Acetylcholine Receptor Structure
Immunopathogenesis of Myasthenia Gravis
Animal Models of Myasthenia Gravis for Preclinical Evaluation
Epidemiology and Genetics of Myasthenia Gravis
Clinical Presentations of Myasthenia Gravis
Ocular Myasthenia
Thymoma-Associated Myasthenia Gravis
Electrodiagnosis of Neuromuscular Junction Disorders
Autoantibody Testing in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases
Treatment of Myasthenia Gravis
Neurocritical Care of Myasthenic Crisis
Thymectomy for Non-thymomatous Myasthenia Gravis
Lambert-Eaton Syndrome
Acquired Neuromyotonia
Congenital Myasthenic Syndromes
Toxic Neuromuscular Transmission Disorders
Predictors of Psychological Health in Myasthenia Gravis
Myasthenia Gravis: Classification and Outcome Measurements
Emerging Therapeutics for Myasthenia Gravis
Clinical Trial Design for Myasthenia Gravis
