Full Description
This volume features expert, refereed reviews of timely topics in each of the areas relevant to addiction science and clinical practice to aid researchers and practitioners interested in addictions. Authors from the United States, EU, Asia and elsewhere provide an international perspective on the problems and practices. Specifically, this volume:
- focuses on topics that are relevant to specific substances but also provides important lessons for addiction to all substances
- provides reviews that are aimed to be useful to specialists in the field and as useful to students as the first criterion allows.
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Contents
Introduction to Addiction reviews 2 / by George R. Uhl 1 Preface to Addiction reviews 2 / by George F. Koob 3
Part I. Medications for addiction and relevant neurotransmitter systems.
Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders / by Christian A. Heidbreder and Amy H. Newman 4
Cocaine-induced neuroadaptations in glutamate transmission : potential therapeutic targets for craving and addiction / by Heath D. Schmidt and R. Christopher Pierce 35
Agonist-like pharmacotherapy for stimulant dependence : preclinical, human laboratory, and clinical studies / by David V. Herin, Craig R. Rush and John Grabowski 76
Part II. Drug and HIV toxicities
Amphetamine toxicities : classical and emerging mechanisms / by Bryan K. Yamamoto, Anna Moszczynska and Gary A. Gudelsky 101
Human immunodeficiency virus-associated neurocognitive disorder : pathophysiology in relation to drug addiction / by Avindra Nath 122
Part III. Physiology.
Synaptic plasticity in the mesolimbic system : therapeutic implications for substance abuse / by Billy T. Chen, F. Woodward Hopf and Antonello Bonci 129
Electrophysiological correlates of abused drugs : relation to natural rewards / by Sam A. Deadwyler 140
Part IV. Imaging.
Neurochemistry of drug action : insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction / by Stephanie C. Licata and Perry F. Renshaw 148
Part V. Development.
Cocaine addiction in mothers : potential effects on maternal care and infant development / by Lane Strathearn and Linda C. Mayes 172
Part VI. Genetics.
Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment / by Vadim Yuferov [and others] 184
Addictions and their familiality in Iceland / by Thorarinn Tyrfingsson [and others] 208
Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs / by Ichiro Sora [and others] 218
Part VII. Behavioral mechanisms.
Conditioned taste aversion learning : implications for animal models of drug abuse / by Catherine M. Davis and Anthony L. Riley 247
Part VIII. Comorbidity.
The strong relationship between bipolar and substance-use disorder : mechanisms and treatment implications / by Alan C. Swann 276
Part IX. Nonsubstance addictions.
Shared brain vulnerabilities open the way for nonsubstance addictions : carving addiction at a new joint? / by Joseph Frascella [and others] 294
Part X. Molecules for addiction.
Regulation of the dopamine transporter : aspects relevant to psychostimulant drugs of abuse / by Kyle C. Schmitt and Maarten E.A. Reith 316
Regulator of G protein-signaling proteins and addictive drugs / by John Traynor 341
Part XI. Epidemiology.
Novel phenotype issues raised in cross-national epidemiological research on drug dependence / by James C. (Jim) Anthony 353
Part XII. Places and institutions.
Office of National Drug Control Policy: A scientist in drug policy in Washington, DC / by Bertha K. Madras. 370
