Full Description
Advances in cancer therapy and transplantation are increasing the numbers of immunocompromised patients throughout the world. This comprehensive review presents state-of-the-art diagnostics for infectious complications in the immunocompromised patients. Providing complementary views of often complex diagnostic challenges, the new edition presents topics such as host biology and antineoplastic and transplantation techniques; the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression; the approach, interpretation, and limitations of the laboratory diagnosis of infections caused by a wide range of etiologic agents; laboratory diagnosis of infections of organ systems, such as respiratory tract, gastrointestinal tract, and central nervous system; and, diagnostic aspects of prosthetic devices and catheters, healthcare-acquired infections, and morphologic considerations (anatomic pathology). New sections discuss tissue pathology, HIV, hepatitis viruses, papilloma and polyoma viruses, and aerobic and anaerobic bacteriology. This book will inform laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of patients who are immunocompromised. Strategies for providing optimal care to this high-risk patient group.The immunocompromised patient population is increasing throughout the world. Major advances in transplantation techniques have expanded access to lifesaving therapies and improved outcomes in these high-risk populations. An understanding of the biology of these infections, host conditions, and the limitations of technologies used to detect and quantify such pathogens is critical to optimal care. This new edition of Diagnostic Microbiology of the Immunocompromised Host covers all aspects of state-of-the-art diagnostics for infectious complications in the immunocompromised patient. Editors Randall Hayden, Karen Carroll, Yi-Wei Tang and Donna Wolk, assembled the contributions of a team of preeminent authors to discuss a broad range of topics, including* relevant aspects of host biology, antineoplastic, and transplantation techniques and the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression * approaches, interpretations, and limitations of laboratory diagnosis of infections by a wide range of specific etiologic agents * laboratory diagnosis of infections of specific organ systems, such as respiratory tract infections, gastrointestinal tract infections, and central nervous system infections * special topics such as prosthetic devices and catheters, healthcare acquired infections, and morphologic considerations (anatomic pathology) * future diagnostic technologies and their potential impact on the field Diagnostic Microbiology of the Immunocompromised Host is a resource for laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of the immunocompromised host.
Contents
ContentsContributors PrefaceForeword1. Overview of Infections in the Immunocompromised HostLesia K. Dropulic and Howard M. LedermanII. LABORATORY DIAGNOSIS: APPROACHES, INTERPRETATIONS, AND LIMITATIONS 2. Human Immunodeficiency VirusWendy S. Armstrong, Jeannette Guarner, Colleen S. Kraft, and Angela M. Caliendo3. Chronic Hepatitis B, C, and DBryan R. Cobb and Alexandra Valsamakis4. CytomegalovirusM. Veronica Dioverti and Raymund R. Razonable5. Epstein-Barr VirusAndrew Nowalk and Michael Green6. Herpes Simplex Virus and Varicella-Zoster VirusMyron J. Levin, Adriana Weinberg, and D. Scott Schmid7. Human Herpesviruses 6A, 6B and 7Henri Agut, Pascale Bonnafous, and Agnes Gautheret-Dejean8. Human PapillomavirusEileen M. Burd and Christina L. Dean9. PolyomavirusesLinda Cook10. AdenovirusMichael G. Ison and Randall T. Hayden11. Respiratory RNA VirusesRichard L. Hodinka12. Enteroviruses and ParechovirusesJames J. Dunn13. Parvovirus B19Marie Louise Landry14. Filamentous FungiMargaret V. Powers-Fletcher, Brian A. Kendall, Allen T. Griffin, and Kimberly E. Hanson15. YeastsSean X. Zhang and Nathan P. Wiederhold16. MycobacteriaPatricia J. Simner, Gail L. Woods, and Nancy L. Wengenack17. Aerobic Actinomycetes of Clinical SignificanceA. Brian Mochon, Den Sussland, and Michael A. Saubolle18. ParasitesElitza S. Theel and Bobbi S. Pritt19. Selected Topics in Aerobic BacteriologyGeraldine Hall and Karen C. Carroll20. Selected Topics in Anaerobic BacteriologyDeirdre L. ChurchIII. LABORATORY DIAGNOSIS: APPROACHES, INTERPRETATIONS AND LIMITATIONS 21. Lower Respiratory Tract InfectionsKaren C. Carroll and La'Tonzia L. Adams22. Genitourinary Tract InfectionsOdaliz Abreu Lanfranco and George J. Alangaden23. Gastrointestinal InfectionsKevin Alby and Irving Nachamkin24. Central Nervous System InfectionsAndrea J. Zimmer, Victoria E. Burke, and Karen C. Bloch25. Bloodstream InfectionsDonna M. Wolk, Raquel M. Martinez, and Diana R. Hernandez26. Skin and Soft Tissue InfectionsAnne Spichler Moffarah, Mayar Al Mohajer, Bonnie L. Hurwitz, and David G. ArmstrongIV. SPECIAL TOPICS27. Prosthetic Device InfectionsRaquel M. Martinez, Thomas R. Bowen, and Michael A. Foltzer28. Hospital-Associated InfectionsEsther Babady29. Surgical Pathologic DiagnosisMary K. Klassen-Fischer and Ronald C. NeafieIndex
