基本説明
Reviews the newest techniques, approaches, and options in the use of microorganisms and other cell culture systems for the manufacture of pharmaceuticals, industrial enzymes and proteins, foods and beverages, fuels and fine chemicals, and other products.
Full Description
A rich array of methods and discussions of productive microbial processes.Reviews of the newest techniques, approaches, and options in the use of microorganisms and other cell culture systems for the manufacture of pharmaceuticals, industrial enzymes and proteins, foods and beverages, fuels and fine chemicals, and other products. Focuses on the latest advances and findings on the current state of the art and science and features a new section on the microbial production of biofuels and fine chemicals, as well as a stronger emphasis on mammalian cell culture methods. Covers new methods that enhance the capacity of microbes used for a wide range of purposes, from winemaking to pharmaceuticals to bioremediation, at volumes from micro- to industrial scale.This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
Table of ContentsSECTION I: Isolation and Screening for Secondary MetabolitesSection Editor, A. T. Bull; Volume Editor, J. E. DaviesIsolation1. New Approaches to Microbial IsolationSlava S. Epstein, Kim Lewis, Dominica Nichols, and Ekaterina Gavrish2. Selective Isolation of ActinobacteriaMichael GoodfellowIdentity / Dereplication3. Taxonomic Characterization of Prokaryotic MicroorganismsGiovanna E. Felis, Sandra Torriani, Johan E. T. van Hylckama Vlieg, and Aharon OrenScreening4. Enzymes from Extreme EnvironmentsDon A. Cowan, Bronwyn M. Kirby, Tracy L. Meiring, Manuel Ferrer, Maria-Eugenia Guazzaroni, Olga V. Golyshina, and Peter N. Golyshin5. Cell-Based Screening Methods for Anti-Infective CompoundsStefano Donadio and Margherita Sosio6. Metabolomics for the Discovery of Novel CompoundsJens C. Frisvad7. Methods To Access Silent Biosynthetic PathwaysRobert H. Cichewicz, Jon C. Henrikson, Xiaoru Wang, and Katie M. Branscum-KirbySECTION II: Fermentation and Cell CultureSection Editor, P. Masurekar; Volume Editor, A. L. Demain8. Miniaturization of FermentationsWouter Duetz, Matthew Chase, and Gerald Bills9. Solid-Phase Fermentation: Aerobic and AnaerobicRamunas Bigelis10. Bacterial Cultivation for Production of Proteins and Other Biological ProductsJoseph Shiloach and Ursula Rinas11. Heterologous Protein Expression in Yeasts and Filamentous FungiNingyan Zhang and Zhiqiang An12. Mammalian Cell Culture for Biopharmaceutical ProductionJinyou Zhang13. Manufacture of Mammalian Cell BiopharmaceuticalsJinyou Zhang14. Plant Cell CultureNancy L. Paiva15. Insect Cell CultureSpiros N. AgathosSECTION III: Genetics, Strain Improvement, and Recombinant ProteinsSection Editor, C. D. Reeves; Volume Editor, R. H. Baltz16. Genetic Engineering of CorynebacteriaMasato Ikeda and Seiki Takeno17. Genetic Manipulation of ClostridiumMarite Bradshaw and Eric A. Johnson18. Genetic Manipulation of MyxobacteriaWesley P. Black, Bryan Julien, Eduardo Rodriguez, and Zhaomin Yang19. Strain Improvement of Escherichia coli To Enhance Recombinant Protein ProductionMichael E. Pyne, Karan S. Sukhija, and C. Perry Chou20. Genetic Engineering Tools for Saccharomyces cerevisiaeVerena Siewers, Uffe, H. Mortensen, and Jens Nielsen21. Protein Expression in Nonconventional YeastsThomas W. Jeffries and James M. Cregg22. Genetics, Genetic Manipulation, and Approaches to Strain Improvement of Filamentous FungiVera Meyer, Arthur F. J. Ram, and Peter J. Punt23. Genetic Manipulations of Mammalian Cells for Protein ExpressionAnne Kantardjieff, Gargi Seth, Scott McIvor, and Wei-Shou HuSECTION IV: Genetic Engineering of Secondary Metabolite SynthesisSection Editor, L. Katz; Volume Editor, R. H. Baltz24. Glycosylation of Secondary Metabolites To Produce Novel CompoundsAndreas Bechthold and Katharina Probst25. Metabolic Engineering of Escherichia coli for the Production of a Precursor to Artemisinin, an Antimalarial DrugChristopher J. Petzold and Jay D. Keasling26. Heterologous Production of Polyketides in Streptomyces coelicolor and Escherichia coliJames T. Kealey27. Genetic Engineering of Acidic Lipopeptide AntibioticsRichard H. Baltz, Kien T. Nguyen, and Dylan C. Alexander28. Genetic Engineering To Regulate Production of Secondary Metabolites in StreptomycesSusan E. Jensen29. Genetic Engineering of Myxobacterial Natural Product Biosynthetic GenesBryan Julien and Eduardo RodriguezSECTION V: Industrial Enzymes, Biocatalysis, and Enzyme EvolutionSection Editor, H. Zhao; Volume Editor, J. E. Davies30. Tools for Enzyme DiscoveryYasuhisa Asano31. Enzyme Engineering: Combining Computational Approaches with Directed EvolutionLouis A. Clark32. Enzyme Engineering by Directed EvolutionManfred T. Reetz33. Industrial Applications of Enzymes as CatalystsNikhil U. Nair, Weng Lin Tang, Dawn Eriksen, and Huimin Zhao34. Biomass-Converting Enzymes and Their Bioenergy ApplicationsFeng Xu35. The Use of Enzymes for Non-Aqueous Organic TransformationsElton P. Hudson, Michael J. Liszka, and Douglas S. Clark36. Enzyme Promiscuity and Evolution of New Protein FunctionsBert van Loo and Florian Hollfelder37. Enzyme Production in Escherichia coliDaniel J. Sayut, Pavan Kumar Reddy Kambam, William G. Herrick, and Lianhong Sun38. Bioprocess DevelopmentLutz Hilterhaus and Andreas LieseSECTION VI: Microbial Fuels (Biofuels) and Fine ChemicalsSection Editor, L. R. Lynd; Volume Editor, A. L. Demain39. Accessing Microbial Communities for Solutions to Biofuels ProductionCarl Abulencia, Steve Wells, Kevin A. Gray, Martin Keller, and Joel A. Kreps40. Micro-Algal Culture as a Feedstock for Bioenergy, Chemicals, and NutritionSusan T. L. Harrison, Melinda J. Griffiths, Nicholas Langley, Caryn Vengadajellum, and Robert P. van Hille41. Metabolic Engineering Strategies for Production of Commodity and Fine Chemicals: Escherichia coli as a Platform OrganismPatrick C. Cirino42. Improving the Microbial Robustness Using Systems BiologyJonathan R. Mielenz and David A. Hogsett43. Bioethanol Production from Lignocellulosics: Some Process Considerations and ProceduresCharles A. Abbas, Wu Li Bao, Kyle E. Beery, Pam Corrington, Consuelo Cruz, Lucas Loveless, Marty Sparks, and Kelli Trei44. Surface Microbiology of Cellulolytic BacteriaAlexandru Dumitrache, Gideon M. Wolfaardt, and Lee R. Lynd45. Physiological and Methodological Aspects of Cellulolytic Microbial CulturesNicolai Panikov and Lee R. LyndSECTION VII: Biological Engineering and Scale-Up of Industrial ProcessesSection Editor, B. Junker; Volume Editor, A. L. Demain46. Raw Materials Selection and Medium Development for Industrial Fermentation ProcessesSamun K. Dahod, Randolph Greasham, and Max Kennedy47. Scale-Up of Microbial Fermentation ProcessXiaoming Yang48. Cell Culture Bioreactors: Controls, Measurements, and Scale-Down ModelWan-Seop Kim49. Continuous CultureAn-Ping Zeng and Jibin Sun50. Advances in Sensor and Sampling Technologies in Fermentation and Mammalian Cell CultureAdeyma Y. Arroyo51. Bioreactor AutomationDavid Hopkins, Melissa St. Amand, and Jack Prior52. Purification and Characterization of ProteinsUlrich Strych and Richard C. Willson