Full Description
While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function. In Molecular Imaging in the Clinical Neurosciences, experts in the field provide the reader with up-to-date information on the basic principles of molecular imaging and its major applications in the clinical neurosciences. Beginning with a section offering a comprehensive review of the methodological foundations from physics, chemistry, and mathematics including mathematical modeling, essential for meaningful data analysis, this detailed volume then continues with sections on the major biological principles and neurochemical targets relevant in current neuroimaging research and the major clinical applications from the fields of psychiatry and neurology. Written for the popular Neuromethods series, this work contains the kind of key description and implementation advice that guarantees successful results.
Authoritative and cutting-edge, Molecular Imaging in the Clinical Neurosciences serves as a helpful source of knowledge for both basic and clinical scientists from psychology, psychiatry, neurology, nuclear medicine, nuclear chemistry, and the associated disciplines, all of which makes molecular imaging such a rewarding, interdisciplinary field of work.
Contents
Instrumentation and Physical Principles.- Molecular Neuroscience and the Quantification of Brain Dynamics.- Radiopharmaceutical Chemistry.- Introduction to the Basics of Magnetic Resonance Imaging.- Quantification of Cerebral Blood Flow.- The Assay of Enzyme Activity by Positron Emission Tomography.- Molecular Imaging Studies of Second Messenger Pathways: Looking Deeper than the Membrane.- Quantification of Neuroreceptors and Neurotransporters.- Measuring Dopamine Synaptic Transmission with Molecular Imaging and Pharmacological Challenges: The State of the Art.- Small Animal Imaging with Positron Emission Tomography (PET).- Emission Imaging in Dementia.- Neurochemical Imaging of Addictive Disorders.- Molecular Imaging of Mood Disorders.- Molecular Imaging in Schizophrenia.- Imaging the Pathophysiology of Ischemic Cerebrovascular Disease.- Molecular Imaging of Brain Tumors.- Molecular Imaging in Parkinson's Disease.- Epilepsy.
