Full Description
RNAs form complexes with proteins and other RNAs. The RNA‑infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‑wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‑based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‑based mechanisms that connect in the RNA infrastructure.
Contents
The RNA Infrastructure: An Introduction to ncRNA Networks.- RNA Interactions.- Plant RNA Silencing in Viral Defence.- MicroRNAs as Post‑Transcriptional Machines and Their Interplay With Cellular Networks.- Spatiotemporal Aspects of MicroRNA‑Mediated Gene Regulation.- Spliceosomal RNA Infrastructure: The Network of Splicing Components and their Regulation by miRNAs.- Construction, Structure and Dynamics of Post‑Transcriptional Regulatory Network Directed by RNA‑Binding Proteins.- Safe Keeping the Message: mRNP Complexes Tweaking after Transcription.- Unexpected functions of tRNA and tRNA Processing Enzymes.- Programmed DNA Elimination in Tetrahymena: A Small RNA‑Mediated Genome Surveillance Mechanism.- Long Noncoding RNA and Epigenomics.- Promoter‑Associated Long Noncoding RNAs Repress Transcription Through a RNA Binding Protein TLS.- RNA Networks in Prokaryotes I: CRISPRs and Riboswitches.- RNA Networks in Prokaryotes II: tRNA Processing and Small RNAs.- Localization of the Bacterial RNA Infrastructure.- Small RNA Discovery and Characterisation in Eukaryotes Using High‑Throughput Approaches.- How Old are RNA Networks?.
