Full Description
The subject of Tumour-Associated Macrophages is of interest in the cancer research community, and this book promises to be among the first to discuss a definitive theory on the role of macrophage in tumor development.
Contents
Preface.- Macrophage Phenotype in Tumors.- Role of Tumour-Associated Macrophages in the Regulation of Tumour Angiogenesis.- The Role of Tumor-Associated Macrophages in Malignant Invasion.- Tumor-Induced Immune Suppression by Myeloid Cells.- TAM: A Moving Clinical Target.- Arginine Metanolism and Tumour Associated Macrophages.- Indoleamine 2,3-dioxygenaseAmino acid metabolism and tumor-associated macrophages: regulation in cancer-associated inflammation and immune escape.- Vascular Endothelial Growth Factor and Tumor-associated macrophages.- TLR Signaling and Tumor-associated Macrophages.- SHIP and Tumor-Associated Macrophages.- NF-KappaB-Mediated Regulation of Tumor-Associated Macrophages: Mechanisms and Signifance.- Role of hypoxia-inducible transcription factors HIF-a for TAM function.- Index.
