Full Description
This expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system and the use of neural stem cells in clinical applications. Integrating new information about the use of development of neural stem cells for clinical applications, Drs. Rao, Carpenter and Vemuri have added additional chapters on neural transplantation and development of neural stem cells using reprogramming technologies. A new chapter on cancer in nervous system delineates how the fundamental biology of neural stem cells informs our understanding of cancer and tumor formation in the nervous system. Special attention is paid to the derivation of neural cells from embryonic stem cells and induced pluripotent stem cells. Authoritative and up-to-date, Neural Development and Stem Cells, 3rd Edition provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.
Contents
Defining Neural Stem Cells and Their Role in Normal Development of the Nervous System.- Embryonic Stem Cells and Neurogenesis.- The Cellular and Molecular Properties of Multipotent Neural Stem Cells.- Multipotent Stem Cells in the Embryonic Nervous System.- Neural Crest Formation and Diversification.- Glial Nature of Adult Neural Stem Cells: Neurogenic Competence in Adult Astrocytes.- Neural Stem Cell Death Regulation in Nervous System Development and Disease.- Stem Cells of the Adult Olfactory Epithelium.- Retinal Stem Cells.- Transdifferentiation in the Nervous System.- Neural and Dopaminergic Differentiation of Human Pluripotent Stem Cells.- Mobilization of Neural stem cells in the Adult Central Nervous System.- Stem Cell Pathways in Brain Tumors.
