Full Description
This second edition comes at a time of a paradigm shift in understanding of the molecular pathology and neuroscience of brain and spinal tumors of childhood and their mechanisms of growth within the developing brain. Excellent collaborative translational networks of researchers are starting to drive change in clinical practise through the need to test many ideas in trials and scientific initiatives. This text reflects the growing concern to understand the impact of the tumour and its treatment upon the full functioning of the child's developing brain and to integrate the judgments of the risks of acquiring brain damage with the risk of death and the consequences for the quality of life for those who survive. Information on the principles of treatment has been thoroughly updated. A chapter also records the extraordinary work done by advocates. All medical and allied professionals involved in any aspect of the clinical care of these patients will find this book an invaluable resource.
Contents
List of Contributors. Introduction. Epidemiology of Childhood Brain Tumors. Clinical Presentation and Associated Syndromes of Brain Tumor. Pediatric Central Nervous System Tumors as Phenotypic Manifestation of Cancer Predisposition Syndromes. Anatomical and Biological Imaging of Pediatric Brain Tumor. Neurosurgical Techniques and Strategies. Radiotherapy for Pediatric Central Nervous System Tumors - Techniques and Strategies. Physical and Cognitive Rehabilitation for Children with Brain and Spinal Tumors. Drug Delivery. Low-grade Glioma Presenting in the Optic Pathways and Hypothalamus (NF1. and Sporadic). Low-grade Glioma: Principles of Diagnosis and Drug Treatment. High-grade Glioma. Diffuse Intrinsic Pontine Glioma. Embryonal Tumors. Ependymoma in Childhood and Adolescence. Germ Cell Tumors of the Central Nervous System. Atypical Teratoid / Rhabdoid Tumors - AT/ RT. Craniopharyngioma. Choroid Plexus Tumors and Meningiomas. Pediatric Spinal Tumors. Late Effects of Treatment for Childhood Brain and Spinal Tumors. The Power of Patient Advocacy in Pediatric Neuro-oncology. Index
