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Full Description
Classical conditioning of the nictitating membrane (NM) eyeblink response in rabbits is a useful model system for the study of the neurobiology of learning and memory. This paradigm that is so well described on a biological level has also been applied to studies of normal development over the life span and to instances of abnormal developmental phenomena.
Eyeblink conditioning has been studied from molecular and neural network perspectives, and the paradigm is of demonstrated utility in elucidating mechanisms in physiology and pharmacology. This model system provides a behavioral paradigm in animals that has a close analog in human behavior.
Perspectives of recent developments in human eyeblink classical conditioning research are presented in the companion volume to this book, Eyeblink Classical Conditioning: Applications in Humans.
Contents
Animal Models in Eyeblink Classical Conditioning.- Discovering the Brain Substrates of Eyeblink Classical Conditioning.- Eyeblink Conditioning Circuitry: Tracing, Lesion, and Reversible Lesion Experiments.- Electrophysiological Recording and Brain Simulation Studies of Eyeblink Conditioning.- Developmental Studies of Eyeblink Conditioning in the Rat.- Alcohol-Induced Damage to the Developing Brain: Functional Approaches Using Classical Eyeblink Conditioning.- Eyeblink Classical Conditioning in Aging Animals.- Cellular Correlates of Eyeblink Classical Conditioning.- Relative Contributions of the Cerebellar Cortex and Cerebellar Nucleus to Eyelid Conditioning.- Neural Network Approaches to Eyeblink Classical Conditioning.- Classical Conditioning of Autonomic and Somatomotor Responses and Their Central Nervous System Substrates.- Motivational Issues in Aversive and Appetitive Conditioning Paradigms.- Cellular Alterations in Hippocampus During Acquisition and Consolidation of Hippocampus-Dependent Trace Eyeblink Conditioning.- Cognitive-enhancing Drugs and Eyeblink Classical Conditioning.
