Investigation and Exploitation of Antibody Combining Sites (Methodological Surveys in Biochemistry and Analysis)

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Investigation and Exploitation of Antibody Combining Sites (Methodological Surveys in Biochemistry and Analysis)

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  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 359 p.
  • 言語 ENG
  • 商品コード 9781468450088
  • DDC分類 540

Contents

#A Antibody Combining Sites, Especially Structure.- #A-1 Antibody combining sites — past, present and future.- #A-2 Variability, modelling and prediction of ?-hairpins with reference to the immunoglobulin fold.- #A-3 Probing the binding sites in crystals of immunoglobulins.- #A-4 Comparative structures of mouse antibody combining sites.- #NC(A) NOTE and COMMENTS related to the foregoing topics*.- #NC(A)-1 An approach to the study of anti-protein antibody combining sites.- #B Production and Characterization of Antibodies, in Contexts such as Receptor Investigation.- #B-1 Investigating the specificity of monoclonal antibodies to protein antigens using ?-galactosidase fusion proteins.- #B-2 Antibody-screening cDNA libraries.- #B-3 Anti-receptor antibodies by the auto-anti-idiotypic route.- #B-4 Production and characterization of anti-morphine anti-idiotypic antibodies.- #B-5 Anti-idiotype antibodies for the study of membrane receptors: the double monoclonal antibody approach.- #NC(B) NOTES and COMMENTS related to the foregoing topics.- #NC(B)-1 Characterization of idiotypes and VH genes of various members of A48-idiotypic network pathway.- #NC(B)-2 Monoclonal internal image anti-idiotypic antibodies of hepatitis B surface antigen.- #NC(B)-3 Structure and expression of genes encoding IgA heavy chains.- #NC(B)-4 Human:mouse antibody-producing transfectoma cell lines.- #NC(B)-5 Different ways to modify monoclonal antibodies.- #NC(B)-6 Restructuring enzymes and antibodies.- #NC(B)-7 Dideoxy mRNA sequencing as a method to analyze antibody diversity.- #NC(B)-8 Effect of multivalent binding on dissociation of monoclonal antibodies from cell surface antigens.- #C Cytoskeletal, Myocyte and Neuronal Studies with Antibodies.- #C-1Immunological approaches and techniques employed in tubulin and microtubule research.- #C-2 Cell-surface events during myogenesis: immunofluorescence analysis using monoclonal antibodies.- #C-3 Differential expression of cell-surface antigens on muscle satellite cells and myoblasts.- #C-4 Cholinergic-specific nerve terminal antigens.- #C-5 Use of antibodies to purify cholinergic nerve terminals.- #NC(C) NOTES and COMMENTS related to the foregoing topics.- #NC(C)-1 An immunological approach to the cell lineage problem in the mammalian CNS.- #NC(C)-2 An enzyme-linked immunosorbent assay for calmodulin.- #NC(C)-3 Intermediate filament diversity as detected by antibodies.- #D Antibody Approaches to Membrane Components Including the T-Cell Receptor.- #D-1 Exploitation of antibodies in the study of cell membranes.- #D-2 Use of polyclonal and monoclonal antibodies in studying complement component C9 as a transmembrane protein.- #D-3 Ca2+-binding proteins located on the cytoplasmic face of the lymphocyte plasma membrane.- #D-4 The T-cell receptor.- #NC(D) NOTES and COMMENTS related to the foregoing topics.- #NC(D)-1 New light on the T-cell receptor in relation to antibody binding sites.- #NC(D)-2 Molecular nature of the T3 antigen of human T lymphocytes.- #NC(D)-3 Organization and expression of the murine T-cell receptor ?-chain gene complex.- #NC(D)-4 Antigen-specific T-cell activation.- #E Antibodies in Relation to Oncology.- #E-1 Requirements by cancer cells for polypeptide growth factors suggest new therapeutic strategies.- #E-2 Monoclonal antibodies to human tumours for targeting cytotoxic drugs.- #E-3 Antigenic modulation as a limiting factor in the treatment of B-cell lymphoma with anti-idiotype antibody.- #E-4 Tumour-associatedcarbohydrate antigens of glycoproteins.- #E-5 Glycolipid antigens: potential in cancer detection and diagnosis.- #NC(E) NOTES and COMMENTS related to the foregoing topics.- #NC(E)-1 Immune surveillance.- #NC(E)-2 WORKSHOP DISCUSSION focused on #E-4, #E-5 & #E-3.- Guidance for 'uninitiated' readers.- Corrections to Vol. 13.

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