Full Description
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio chemical cytology, and high resolution microscopy and spec troscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Contents
1Bunyaviridae.- 1. Introduction.- 2. Structural Components and Their Functions.- 3. Replication of Bunyaviruses.- 4. Genetics.- 5. Defective Interfering Virus.- 6. Conclusions.- 7. References.- 2Arenaviruses.- 1. Introduction.- 2. Historical Considerations.- 3. Pathobiology.- 4. Morphologic and Physical Properties.- 5. Proteins.- 6. Nucleic Acids.- 7. Internal Components of the Virus.- 8. Replication in Cultured Cells.- 9. Interference and Defective Interfering Particles.- 10. Concluding Remarks.- 11. References.- 3Coronaviridae.- 1. Introduction.- 2. Virions.- 3. Growth Properties in Cell and Organ Culture.- 4. Multiplication of Virus.- 5. Alteration in Host Cell Metabolism.- 6. Defective Virus and Viral Interference.- 7. Pathogenesis of Coronavirus Disease.- 8. Persistent Infections.- 9. Genetics.- 10. Conclusion.- 11. References.- 4Caliciviruses.- 1. Introduction and Classification.- 2. Natural History and Disease Aspects.- 3. Antigenic Aspects.- 4. Caliciviruses in Cultured Cells.- 5. The Virion.- 6. Defective Interfering Virus.- 7. Concluding Remarks.- 8. Addendum.- 9. References.- 5Orbiviruses.- 1. Introduction.- 2. Propagation and Assay Systems.- 3. The Virion.- 4. Replication.- 5. Antigenic Properties.- 6. Epizootiology.- 7. Concluding Remarks.- 8. References.- 6Icosahedral Cytoplasmic Deoxyriboviruses.- 1. Introduction.- 2. Classification and General Biological Properties of Icosahedral Cytoplasmic Deoxyriboviruses.- 3. Size, Morphology, and Structure.- 4. Physical Properties.- 5. Chemical Composition.- 6. Replication.- 7. Conclusions and Prospects for the Future.- 8. References.- 7Fish Viruses and Viral Infections.- 1. Introduction.- 2. Fish Herpesviridae.- 3. Fish Iridoviridae.- 4. Fish Reoviridae.- 5. Fish Rhabdoviridae.- 6. Fish Retroviridae.- 7. Unclassified and Putative Fish Viruses Associated with Neoplasia.- 8. Unclassified and Putative Fish Viruses.- 9. References.- 8Viruses of Human Hepatitis A and B.- 1. Introduction: Recognition of Hepatitis Viruses.- 2. Hepatitis B Virus (HBV).- 3. Course of HBV Infection.- 4. Disease Associated with HBV Infection.- 5. Epidemiology of HBV.- 6. Hepatitis A Virus (HAV).- 7. Course of HAV Infection.- 8. Immunity to HAV.- 9. Disease Associated with HAV Infection.- 10. Epidemiology of HAV Infections.- 11. References.
