Full Description
Radiation therapy of cutaneous cancers and other dermatologic disorders is not covered adequately in many current textbooks of dermatology and radiation oncology. This book is intended to fill that gap. Both text and illustrations are oriented toward the practical aspects of radiation therapy. The beginner will find a concise introduction to physical and biological principles, selec tion of radiation factors, dose definitions, indications for treatment, and radiation seque lae. The experienced dermatologist and radiation oncologist will find a detailed discussion of specific indications for various radiation techniques in different body regions. A special effort was made to add pertinent references to the world literature for those who wish to pursue particular topics still further. We have tried to include all major American and European publications of the last 20 years in our bibliography of more than 500 refer ences, and we also have attempted to review the most important scientific papers on prin ciples and practice of ionizing radiation therapy in a constructive way. We are grateful to Professor Gorson, Dr. Breneman, and Professor Lindel6f, who generously contributed chapters in their areas of expertise despite their many other com mitments.
Contents
1. Physical Aspects of Dermatologic Radiotherapy.- X-Ray Phenomena.- Dosimetry.- Depth Dose Calculations.- Summary.- References.- 2. Radiobiology.- Interaction of Radiation with Matter.- Biologic Effects.- Cell Kinetics.- Radiosensitivity Modifiers.- References.- 3. Radiation Reactions and Sequelae.- Reversible Radiation Effects.- Irreversible Radiation Effects.- References.- 4. Chronic Radiation Effects and Radiation Protection.- Nonstochastic Effects.- Stochastic Effects.- Genetic Effects.- Radiation Protection and Shielding.- References.- 5. Treatment Planning: Selection of Physical Factors and Radiation Techniques.- Physical Factors.- Radiation Techniques.- X-Ray Machines and Radiation Sources.- Quality of Radiation.- Selection of Physical Factors.- Definitions of Radiation Doses.- References.- 6. Radiation Therapy of Cutaneous Carcinomas: Radiation Techniques and Dose Schedules.- General Considerations.- Selection of Radiation Quality.- Radiation Dose.- Results of Radiation Therapy.- Radiation Sequelae.- References.- 7. Radiation Therapy of Cutaneous Carcinomas: Indications in Specific Anatomic Regions.- Carcinoma of the Nose.- Carcinoma of the Eyelid.- Carcinoma of the Ear.- Carcinoma of the Lip.- Carcinoma of Other Regions.- References.- 8. Radiation Therapy of Other Cutaneous Tumors.- Keratoacanthoma.- Kaposi's Sarcoma.- Epidemic Kaposi's Sarcoma (Acquired Immunodeficiency Syndrome).- Bowen's Disease.- Cutaneous Lymphomas (Mycosis Fungoides).- Widespread Lesions.- References.- 9. Radiation Therapy of Melanomas.- General Considerations.- Experimental Findings.- Review of the Literature.- References.- 10. Radiation Therapy of Benign Tumors, Hyperplasias, and Dermatoses.- General Considerations.- Lymphocytoma Cutis.- Keloid.- Eczema/Dermatitis.- Psoriasis.-Other Rare Indications for Radiotherapy.- References.- 11. Electron-Beam Therapy.- Physical and Biologic Interactions.- Production of Electron-Beam Radiation.- Total Skin Electron Irradiation.- Localized Skin Lesions, Including Basal and Squamous Cell Skin Carcinomas.- References.- 12. Grenz-Ray Therapy.- History.- Physics.- Biologic Effects.- Side Effects.- Indications.- Dosage.- Radiation Protection.- References.
