Full Description
As appropriately outlined in the first chapter in cells was pioneered in Holland by Van Loghem and part II in this book, the history of contemporary Van Rood, and it led eventually to the discovery of blood transfusion is only three-quarters of a cen- the HLA system and its subsequent explosive de- tury old. On the surface, there is not much left in velopment. In biochemistry, the work on the ABO common between an arm to arm blood transfer and MN blood group substances has provided carried out as an heroic measure in the twenties, pointers to general features of the biosynthesis and when patient or donor had to be weighed in order role of glycolipids and glycoproteins in the cell for the physician to decide when to stop, and blood membrane, and the identification of serological component therapy of today, when several patients specificities associated with specific oligo sac- can benefit from appropriately measured and stan- chari des has proven for the first time how gene dardized amounts of various purified blood frac- products that are not proteins can exhibit Men- tions. Yet, the basic principles of blood transfusion delian inheritance.
Contents
One: Pathophysiology.- 1. Role of cell culture in the management of haematological diseases.- 2. Oxygen transport to the tissue and blood viscosity.- 3. Infection prevention in neutropenic patients.- 4. Apheresis units: designs and future applications.- 5. Platelets for transfusion: collection, storage and clinical efficacy.- 6. Leukapheresis: clinical experience and post-transfusion control.- 7. Plasma proteins for therapeutic use: past, present and future.- 8. Clinical significance of tissue antigens.- 9. Clinical significance of red cell blood groups.- 10. The crossmatch: how much is enough?.- 11. Isoimmunisation in pregnancy: diagnosis, treatment and prevention.- 12. Immune plasma for immunoglobulin.- Two: Clinical Practice.- 1. Blood and blood components: uses and abuses.- 2. Massive transfusion and its effects in clinical practice.- 3. Diagnosis of bleeding disorders.- 4. Treatment of the haemophilias.- 5. Advances in the treatment of thrombocytopenia.- 6. Red cell therapy.- 7. Blood transfusion in sickle cell disease.- 8. Supportive care in leukemia treatment.- 9. Immunosuppression and oncology.- 10. Use of immunoglobulins.- 11. Bone marrow transplantation (BMT).- 12. Transfusion support and obstetrical haemorrhage.- 13. Cardiac operations and transfusion requirements.- 14. Supportive therapy for liver transplantation.- 15. Supportive therapy in the new born.- 16. Therapeutic plasma exchange.- 17. Transfusion related morbidity and mortality in the intensive care facility.- 18. Infections transmitted by blood transfusion.- Three: Future Trends.- 1. Hepatitis B in pregnancy.- 2. Interferons: past, present and future.- 3. The use of antibody in the malignant blood diseases.- 4. Therapeutic approaches to abnormalities of blood rheology in vascular disease.- 5. Can wesupport comprehensive home care for haemophiliacs?.- 6. Transfusion support in a community disaster.- 7. Comprehensive haemotherapy program for developing countries.- 8. Artificial blood substitutes.
