Full Description
The purpose of this book is to provide an update both on the present management of proliferative vitreoretinopathy (PVR) and on clinical and experimental research being done to control this disease. The book is divided into three parts. The first part deals with the current management of PVR. The Retina Society Classification of PVR is based in part on a gradation of severity from minimal to massive; therefore, this book attempts to correlate the management of PVR with its severity. The treatment of PVR of varying degrees of severity, from mild to the most severe form, is described by those authors with extensive experience with this spectrum of cases. Much progress has been made in the management of severe PVR as a result of vitreous injections, vitrectomy, periretinal membrane surgery, and retinal surgery. Authors in this book show that in mild and moderately severe PVR excellent results can be obtained with techniques that are less invasive and possibly less likely to stimulate further abnormal cellular proliferation. The new modalities for treatment of PVR are discussed by authors having extensive experience with them. The current status of pharmacological treatment and new concepts of the pathobiology of PVR are discussed. The second part of the book deals with questions frequently encountered in the management of PVR. These questions are answered by a panel of experts including Gary W. Abrams, Steven T. Charles, William H. Havener, Robert Machemer, Charles L. Schepens, and Walter H. Stern.
Contents
I Proliferative Vitreoretinopathy (PVR): An Update.- 1 PVR: An Overview.- 2 Pathobiology of PVR.- 3 Anterior PVR Part I: Clinical Findings and Management.- II: Clinicopathologic, Light Microscopic, and Ultrastructural Findings.- 4 Management of Posterior PVR.- 5 Management of Retinal Detachment with Moderate PVR.- 6 Surgical Treatment of PVR.- 7 Management of Severe (Grade D) PVR with Mechanical Fixation of the Retina.- 8 Treatment of Traumatic Traction Detachment in Eyes with PVR Severe Damage to the Anterior Segment.- 9 Pharmacologic Treatment of PVR.- 10 Intraocular Silicone Oil Versus Gas in the Management of PVR: A Multicenter Clinical Study.- II PVR: A Discussion of Common Concerns.- PVR: A Discussion of Common Concerns.- III PVR: Reports of Current Clinical and Research Studies.- 11 Photographic Documentation and Grading of PVR.- 12 PVR: An Analysis of Factors in Retinal Detachments Using the PVR Classification.- 13 PVR in Labrador Retrievers.- 14 Stimulation of Retinal Pigment Epithelium (RPE) Proliferation and Migration of Macrophages.- 15 Liposome-Encapsulated 5-Fluorouracil: A New Approach to PVR.- 16 Five Fluorouracil Buckles and Retinal Pigment Epithelium (RPE) Proliferation In Situ.- 17 Low-Dose Irradiation Inhibits Retinal Pigment Epithelial Cell Proliferation.- 18 Enzyme-Assisted Vitrectomy: An Update.- 19 Perfluoropropane Gas, Modified Panretinal Photocoagulation and Vitrectomy in the Management of Severe PVR.- 20 Tolerance of Perfluorocarbons, Fluorosilicone, and Silicone Liquids in the Vitreous.- 21 Carmustine (BCNU) in Silicone Oil Prevents Proliferation of Cultured Cells.- 22 Silicone Oil for Management of PVR: Comparison of Six-Month and Two-Year Results.- 23 Silicone Oil in the Management of Retinal Detachment with Acute Retinal Necrosis.- 24 High-Density Fluorosilicone Oil in Vitreous Surgery.- 25 Retinol and Cholesterol in Intraocular Silicone and Fluorosilicone Oils.- 26 Vitrectomy and 360o Scleral Buckling in the Treatment of PVR.- 27 Postvitrectomy Redetachment in PVR Due to a Pars Plana Hole at the Inferotemporal Sclerotomy Site.
