Full Description
After more than 75 years, Nelson Textbook of Pediatrics remains your indispensable source for definitive, state-of-the-art answers on every aspect of pediatric care. Embracing the new advances in science as well as the time-honored art of pediatric practice, this classic reference provides the essential information that practitioners and other care providers involved in pediatric health care throughout the world need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Brand-new chapters and comprehensive revisions throughout ensure that you have the most recent information on diagnosis and treatment of pediatric diseases based on the latest recommendations and methodologies. "The coverage of such a wide range of subjects relating to child health makes this textbook still the gold standard and companion for all pediatricians across the world." Reviewed by Neel Kamal, Sept 2015"All in all, this is an excellent and detailed paediatric review textbook which represents excellent value for money..truly a textbook for the global community" Reviewed by glycosmedia.com, Sept 2015Form a definitive diagnosis and create the best treatment plans possible using evidence-based medicine and astute clinical experiences from leading international authors-many new to this edition.A NEW two-volume layout provides superior portability and exceptional ease of use. Gain a more complete perspective. Along with a broader emphasis on imaging and molecular diagnoses and updated references, the new edition includes an increased focus on international issues to ensure relevance in pediatrics practice throughout the world.Effectively apply the latest techniques and approaches with complete updates throughout 35 new chapters, including: Innovations in Addressing Child Health and Survival in Low Income Settings; Developmental Domains and Theories of Cognition; The Reggio Emilia Educational Approach Catatonia ; Refeeding Syndrome; Altitude-associated Illness; Genetic Approaches to Rare and Undiagnosed Diseases; Healthcare?Associated Infections; Intrapartum and Peripartum Infections; Bath salts and other drugs of abuse; Small Fiber Polyneuropathy; Microbiome; Kingella kingae; Mitochondrial Neurogastrointestinal Encephalomyopathy; Nonalcoholic Fatty Liver Disease; Plagiocephaly; CNS Vasculitis; Anterior Cruciate Ligament Rupture; and Sports-Related Traumatic Brain Injury.Recognize, diagnose, and manage genetic and acquired conditions more effectively. A new Rehabilitation section with 10 new chapters, including: Evaluation of the Child for Rehabilitative Services; Severe Traumatic Brain Injury; Spinal Cord Injury and Autonomic Crisis Management; Spasticity; Birth Brachial Plexus Palsy; Traumatic and Sports-Related Injuries; Meningomyelocele; Health and Wellness for Children with Disabilities.Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Contents
VOLUME 1PART IThe Field of Pediatrics5 MAXIMIZING CHILDREN'S HEALTH: ?SCREENING, ANTICIPATORY GUIDANCE, AND COUNSELINGPART IIGrowth, Development, and Behavior6 OVERVIEW AND ASSESSMENT OF ?VARIABILITY7 COGNITIVE DEVELOPMENT: DOMAINS AND THEORIES9 THE NEWBORN10 THE FIRST YEAR11 THE SECOND YEAR12 THE PRESCHOOL YEARS13 MIDDLE CHILDHOOD14 ADOLESCENCE16 DEVELOPMENTAL-BEHAVIORAL SCREENING AND SURVEILLANCE17 CHILDCARE: HOW PEDIATRICIANS CAN SUPPORT CHILDREN AND FAMILIES18 LOSS, SEPARATION, AND BEREAVEMENT19 SLEEP MEDICINEPART IIIBehavioral and Psychiatric Disorders20 ASSESSMENT AND INTERVIEWING22 SOMATIC SYMPTOM AND RELATED DISORDERS23 RUMINATION AND PICA24 MOTOR DISORDERS AND HABITS25 ANXIETY DISORDERS26 MOOD DISORDERS27 SUICIDE AND ATTEMPTED SUICIDE28 EATING DISORDERS29 DISRUPTIVE, IMPULSE-CONTROL, AND CONDUCT DISORDERS30 AUTISM SPECTRUM DISORDER31 CHILDHOOD PSYCHOSES PART IVLearning Disorders33 ATTENTION-DEFICIT/HYPERACTIVITY DISORDER34 DYSLEXIA35 LANGUAGE DEVELOPMENT AND COMMUNICATION DISORDERS36 INTELLECTUAL DISABILITYPART VChildren with Special Needs37 ADOPTION38 FOSTER AND KINSHIP CARE40 ABUSED AND NEGLECTED CHILDREN43 PEDIATRIC PALLIATIVE CAREPART VINutrition44 NUTRITIONAL REQUIREMENTS45 FEEDING HEALTHY INFANTS, CHILDREN, ?AND ADOLESCENTS46 NUTRITION, FOOD SECURITY, AND HEALTH47 OVERWEIGHT AND OBESITY48 VITAMIN A DEFICIENCIES AND EXCESS49 VITAMIN B COMPLEX DEFICIENCIES AND EXCESS50 VITAMIN C (ASCORBIC ACID)51 RICKETS AND HYPERVITAMINOSIS D52 VITAMIN E DEFICIENCY53 VITAMIN K DEFICIENCY54 MICRONUTRIENT MINERAL DEFICIENCIESPART VIIFluid and Electrolyte Disorders55 ELECTROLYTE AND ACID-BASE DISORDERS56 MAINTENANCE AND REPLACEMENT THERAPY57 DEFICIT THERAPYPART VIIIPediatric Drug Therapy59 PEDIATRIC PHARMACOGENETICS, PHARMACOGENOMICS, AND PHARMACOPROTEOMICS61 ANESTHESIA, PERIOPERATIVE CARE, AND SEDATION62 PEDIATRIC PAIN MANAGEMENT63 POISONING64 COMPLEMENTARY THERAPIES AND INTEGRATIVE MEDICINEPART IXThe Acutely Ill Child66 EMERGENCY MEDICAL SERVICES FOR CHILDREN67 PEDIATRIC EMERGENCIES AND RESUSCITATION68 NEUROLOGIC EMERGENCIES AND STABILIZATION69 SYNCOPE70 SHOCK71 RESPIRATORY DISTRESS AND FAILURE74 DROWNING AND SUBMERSION INJURY75 BURN INJURIES76 COLD INJURIESPART XHuman Genetics79 THE HUMAN GENOME81 CYTOGENETICSPART XIMetabolic Disorders88 MUCOPOLYSACCHARIDOSES90 HUTCHINSON-GILFORD PROGERIA SYNDROME91 THE PORPHYRIAS92 HYPOGLYCEMIAPART XIIThe Fetus and the Neonatal Infant94 THE NEWBORN INFANT95 HIGH-RISK PREGNANCIES96 THE FETUS97 THE HIGH-RISK INFANT99 NERVOUS SYSTEM DISORDERS100 DELIVERY ROOM EMERGENCIES101 RESPIRATORY TRACT DISORDERS102 DIGESTIVE SYSTEM DISORDERS103 BLOOD DISORDERS104 GENITOURINARY SYSTEM105 THE UMBILICUS106 METABOLIC DISTURBANCES107 THE ENDOCRINE SYSTEM108 DYSMORPHOLOGYPART XIIIAdolescent Medicine110 ADOLESCENT DEVELOPMENT113 VIOLENT BEHAVIOR114 SUBSTANCE ABUSE115 THE BREAST116 MENSTRUAL PROBLEMS117 CONTRACEPTION118 ADOLESCENT PREGNANCY119 ADOLESCENT RAPE120 SEXUALLY TRANSMITTED INFECTIONS121 CHRONIC FATIGUE SYNDROMEImmunologySection 2 THE T-, B-, AND NK-CELL SYSTEMS123 T LYMPHOCYTES, B LYMPHOCYTES, AND NATURAL KILLER CELLS126 PRIMARY COMBINED ANTIBODY AND CELLULAR IMMUNODEFICIENCIESSection 3 THE PHAGOCYTIC SYSTEM127 NEUTROPHILS128 MONOCYTES, MACROPHAGES, AND DENDRITIC CELLS129 EOSINOPHILS131 LEUKOPENIA132 LEUKOCYTOSISSection 4 THE COMPLEMENT SYSTEM133 THE COMPLEMENT SYSTEMSection 5 HEMATOPOIETIC STEM CELL TRANSPLANTATIONTRANSPLANTATION136 HEMATOPOIETIC STEM CELL TRANSPLANTATION FROM ALTERNATIVE SOURCES AND DONORS137 GRAFT-VERSUS-HOST DISEASE, REJECTION, AND VENOOCCLUSIVE DISEASE138 INFECTIOUS COMPLICATIONS OF ?HEMATOPOIETIC STEM CELL TRANSPLANTATIONPART XVAllergic Disorders143 ALLERGIC RHINITIS144 CHILDHOOD ASTHMA145 ATOPIC DERMATITIS (ATOPIC ECZEMA)146 INSECT ALLERGY147 OCULAR ALLERGIES148 URTICARIA (HIVES) AND ANGIOEDEMA149 ANAPHYLAXIS150 SERUM SICKNESSRheumatic Diseases of Childhood155 JUVENILE IDIOPATHIC ARTHRITIS156 ANKYLOSING SPONDYLITIS AND OTHER SPONDYLOARTHRITIDES157 REACTIVE AND POSTINFECTIOUS ARTHRITIS158 SYSTEMIC LUPUS ERYTHEMATOSUS159 JUVENILE DERMATOMYOSITIS160 SCLERODERMA AND RAYNAUD PHENOMENON161 BEHCET DISEASE162 SJOEGREN SYNDROME163 HEREDITARY PERIODIC FEVER SYNDROMES AND OTHER SYSTEMIC AUTOINFLAMMATORY DISEASES164 AMYLOIDOSIS165 SARCOIDOSIS166 KAWASAKI DISEASE167 VASCULITIS SYNDROMES168 MUSCULOSKELETAL PAIN SYNDROMES169 MISCELLANEOUS CONDITIONS ASSOCIATED WITH ARTHRITISPART XVIIInfectious DiseasesSection 1 GENERAL CONSIDERATIONS170 DIAGNOSTIC MICROBIOLOGY171 THE MICROBIOME AND PEDIATRIC HEALTHSection 2 PREVENTIVE MEASURES172 IMMUNIZATION PRACTICES173 INFECTION PREVENTION AND CONTROL174 CHILDCARE AND COMMUNICABLE ? DISEASES175 HEALTH ADVICE FOR CHILDREN TRAVELING INTERNATIONALLY176 FEVER177 FEVER WITHOUT A FOCUS179 INFECTION ASSOCIATED WITH MEDICAL DEVICESSection 3 ANTIBIOTIC THERAPYSection 4 GRAM-POSITIVE BACTERIAL INFECTIONS181 STAPHYLOCOCCUS182 STREPTOCOCCUS PNEUMONIAE (PNEUMOCOCCUS)183 GROUP A STREPTOCOCCUS184 GROUP B STREPTOCOCCUS185 NON-GROUP A OR B STREPTOCOCCI186 ENTEROCOCCUS187 DIPHTHERIA (CORYNEBACTERIUM DIPHTHERIAE)188 LISTERIA MONOCYTOGENES189 ACTINOMYCES190 NOCARDIASection 5 GRAM-NEGATIVE BACTERIAL INFECTIONS191 NEISSERIA MENINGITIDIS (MENINGOCOCCUS)192 NEISSERIA GONORRHOEAE (GONOCOCCUS)193 KINGELLA KINGAE194 HAEMOPHILUS INFLUENZAE195 CHANCROID (HAEMOPHILUS DUCREYI)196 MORAXELLA CATARRHALIS197 PERTUSSIS (BORDETELLA PERTUSSIS AND BORDETELLA PARAPERTUSSIS)198 SALMONELLA199 SHIGELLA200 ESCHERICHIA COLI201 CHOLERA202 CAMPYLOBACTER203 YERSINIA204 AEROMONAS AND PLESIOMONAS205 PSEUDOMONAS, BURKHOLDERIA, AND STENOTROPHOMONAS206 TULAREMIA (FRANCISELLA TULARENSIS)207 BRUCELLA208 LEGIONELLA209 BARTONELLASection 6 ANAEROBIC BACTERIAL INFECTIONS210 BOTULISM (CLOSTRIDIUM BOTULINUM)211 TETANUS (CLOSTRIDIUM TETANI)212 CLOSTRIDIUM DIFFICILE INFECTION213 OTHER ANAEROBIC INFECTIONSSection 7 MYCOBACTERIAL INFECTIONS215 TUBERCULOSIS (MYCOBACTERIUM TUBERCULOSIS)216 HANSEN DISEASE (MYCOBACTERIUM LEPRAE)217 NONTUBERCULOUS MYCOBACTERIASection 8 SPIROCHETAL INFECTIONS218 SYPHILIS (TREPONEMA PALLIDUM)219 NONVENEREAL TREPONEMAL INFECTIONS220 LEPTOSPIRA221 RELAPSING FEVER (BORRELIA)222 LYME DISEASE (BORRELIA BURGDORFERI)Section 9 MYCOPLASMAL INFECTIONS223 MYCOPLASMA PNEUMONIAE,224 GENITAL MYCOPLASMAS (MYCOPLASMA HOMINIS, MYCOPLASMA GENITALIUM, AND UREAPLASMAUREALYTICUM)Section 10 CHLAMYDIAL INFECTIONS225 CHLAMYDIA (CHLAMYDOPHILA) PNEUMONIAE226 CHLAMYDIA TRACHOMATIS227 PSITTACOSIS (CHLAMYDIA PSITTACI)Section 11 RICKETTSIAL INFECTIONS228 SPOTTED FEVER GROUP RICKETTSIOSES229 SCRUB TYPHUS (ORIENTIA TSUTSUGAMUSHI)230 TYPHUS GROUP RICKETTSIOSES,231 EHRLICHIOSIS AND ANAPLASMOSIS232 Q FEVER (COXIELLA BURNETII)Section 12 FUNGAL INFECTIONS234 CANDIDA235 CRYPTOCOCCUS NEOFORMANS236 MALASSEZIA237 ASPERGILLUS238 HISTOPLASMOSIS (HISTOPLASMA CAPSULATUM)239 BLASTOMYCOSIS (BLASTOMYCES DERMATITIDIS)240 COCCIDIOIDOMYCOSIS (COCCIDIOIDES SPECIES)241 PARACOCCIDIOIDES BRASILIENSIS242 SPOROTRICHOSIS (SPOROTHRIX SCHENCKII)243 ZYGOMYCOSIS (MUCORMYCOSIS)244 PNEUMOCYSTIS JIROVECISection 13 VIRAL INFECTIONS246 MEASLES247 RUBELLA248 MUMPS249 POLIOVIRUSES250 NONPOLIO ENTEROVIRUSES251 PARVOVIRUSES252 HERPES SIMPLEX VIRUS253 VARICELLA-ZOSTER VIRUS254 EPSTEIN-BARR VIRUS255 CYTOMEGALOVIRUS256 ROSEOLA (HUMAN HERPESVIRUSES 6 AND 7)257 HUMAN HERPESVIRUS 8258 INFLUENZA VIRUSES259 PARAINFLUENZA VIRUSES260 RESPIRATORY SYNCYTIAL VIRUS261 HUMAN METAPNEUMOVIRUS262 ADENOVIRUSES263 RHINOVIRUSES264 CORONAVIRUSES265 ROTAVIRUSES, CALICIVIRUSES, AND ASTROVIRUSES266 HUMAN PAPILLOMAVIRUSES268 ARBOVIRAL INFECTIONS OUTSIDE NORTH AMERICA269 DENGUE FEVER AND DENGUE HEMORRHAGIC FEVER270 YELLOW FEVER271 EBOLA AND OTHER VIRAL HEMORRHAGIC FEVERS272 LYMPHOCYTIC CHORIOMENINGITIS VIRUS273 HANTAVIRUS PULMONARY SYNDROME274 RABIES275 POLYOMAVIRUSES276 ACQUIRED IMMUNODEFICIENCY SYNDROME (HUMAN IMMUNODEFICIENCY VIRUS)277 HUMAN T-LYMPHOTROPIC VIRUSES (1 AND 2)278 TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIESSection 14 ANTIPARASITIC THERAPYSection 15 PROTOZOAN DISEASES280 PRIMARY AMEBIC MENINGOENCEPHALITIS281 AMEBIASIS282 GIARDIASIS AND BALANTIDIASIS283 CRYPTOSPORIDIUM, ISOSPORA, CYCLOSPORA, AND MICROSPORIDIA284 TRICHOMONIASIS (TRICHOMONAS VAGINALIS)285 LEISHMANIASIS (LEISHMANIA)286 AFRICAN TRYPANOSOMIASIS (SLEEPING SICKNESS; TRYPANOSOMA BRUCEI COMPLEX)287 AMERICAN TRYPANOSOMIASIS (CHAGAS DISEASE; TRYPANOSOMA CRUZI)288 MALARIA (PLASMODIUM)289 BABESIOSIS (BABESIA)290 TOXOPLASMOSIS (TOXOPLASMA GONDII)Section 16 HELMINTHIC DISEASES291 ASCARIASIS (ASCARIS LUMBRICOIDES)292 HOOKWORMS (NECATOR AMERICANUS AND ANCYLOSTOMA SPP.)293 TRICHURIASIS (TRICHURIS TRICHIURA)294 ENTEROBIASIS (ENTEROBIUS VERMICULARIS)295 STRONGYLOIDIASIS (STRONGYLOIDES STERCORALIS)296 LYMPHATIC FILARIASIS (BRUGIA MALAYI, BRUGIA TIMORI, AND WUCHERERIA BANCROFTI), 1739297 OTHER TISSUE NEMATODES298 TOXOCARIASIS (VISCERAL AND OCULAR LARVA MIGRANS)299 TRICHINELLOSIS (TRICHINELLA SPIRALIS)300 SCHISTOSOMIASIS (SCHISTOSOMA)301 FLUKES (LIVER, LUNG, AND INTESTINAL)302 ADULT TAPEWORM INFECTIONS303 CYSTICERCOSIS304 ECHINOCOCCOSIS (ECHINOCOCCUS GRANULOSUS AND ECHINOCOCCUS MULTILOCULARIS)VOLUME 2PART XVIIIThe Digestive System305 NORMAL DIGESTIVE TRACT PHENOMENASection 2 THE ORAL CAVITY309 MALOCCLUSION310 CLEFT LIP AND PALATE311 SYNDROMES WITH ORAL MANIFESTATIONS312 DENTAL CARIES313 PERIODONTAL DISEASES314 DENTAL TRAUMASection 3 THE ESOPHAGUS319 CONGENITAL ANOMALIES321 DYSMOTILITY322 HIATAL HERNIA323 GASTROESOPHAGEAL REFLUX DISEASE324 EOSINOPHILIC ESOPHAGITIS AND NON-GASTROESOPHAGEAL REFLUX DISEASE ESOPHAGITIS325 ESOPHAGEAL PERFORATION326 ESOPHAGEAL VARICES327 INGESTIONSSection 4 STOMACH AND INTESTINES328 NORMAL DEVELOPMENT, STRUCTURE, AND FUNCTION330 INTESTINAL ATRESIA, STENOSIS, AND MALROTATIONOMPHALOMESENTERIC DUCT332 MOTILITY DISORDERS AND HIRSCHSPRUNG DISEASE333 ILEUS, ADHESIONS, INTUSSUSCEPTION, AND CLOSED-LOOP OBSTRUCTIONS336 INFLAMMATORY BOWEL DISEASE337 EOSINOPHILIC GASTROENTERITIS341 CHRONIC DIARRHEA342 FUNCTIONAL ABDOMINAL PAIN (NONORGANIC CHRONIC ABDOMINAL ?PAIN)343 ACUTE APPENDICITIS346 INGUINAL HERNIASSection 5 EXOCRINE PANCREAS347 EMBRYOLOGY, ANATOMY, AND ?PHYSIOLOGY348 PANCREATIC FUNCTION TESTS351 PANCREATITIS353 PANCREATIC TUMORSSection 6 THE LIVER AND BILIARY SYSTEM356 CHOLESTASIS358 VIRAL HEPATITIS359 LIVER ABSCESS360 LIVER DISEASE ASSOCIATED WITH SYSTEMIC DISORDERS361 MITOCHONDRIAL HEPATOPATHIES362 AUTOIMMUNE HEPATITIS363 DRUG- AND TOXIN-INDUCED LIVER INJURY364 FULMINANT HEPATIC FAILURE367 PORTAL HYPERTENSION AND VARICES368 LIVER TRANSPLANTATIONSection 7 PERITONEUM369 MALFORMATIONS370 ASCITES371 PERITONITIS372 EPIGASTRIC HERNIAPART XIXRespiratory SystemSection 1 DEVELOPMENT AND FUNCTION373 RESPIRATORY PATHOPHYSIOLOGY AND REGULATION375 SUDDEN INFANT DEATH SYNDROME378 NASAL POLYPS379 THE COMMON COLD380 SINUSITIS381 ACUTE PHARYNGITIS382 RETROPHARYNGEAL ABSCESS, LATERAL PHARYNGEAL (PARAPHARYNGEAL) ABSCESS, AND PERITONSILLAR CELLULITIS/ABSCESS383 TONSILS AND ADENOIDS385 ACUTE INFLAMMATORY UPPER AIRWAY OBSTRUCTION (CROUP, EPIGLOTTITIS, LARYNGITIS, AND BACTERIAL TRACHEITIS)388 LARYNGOTRACHEAL STENOSIS AND SUBGLOTTIC STENOSIS389 BRONCHOMALACIA AND ?TRACHEOMALACIA391 WHEEZING, BRONCHIOLITIS, AND BRONCHITIS392 EMPHYSEMA AND OVERINFLATION393 ?1-ANTITRYPSIN DEFICIENCY AND EMPHYSEMA394 OTHER DISTAL AIRWAY DISEASES396 PULMONARY EDEMA397 ASPIRATION SYNDROMES398 CHRONIC RECURRENT ASPIRATION399 IMMUNE AND INFLAMMATORY LUNG DISEASE400 COMMUNITY-ACQUIRED PNEUMONIA401 BRONCHIECTASIS402 PULMONARY ABSCESS403 CYSTIC FIBROSIS404 PRIMARY CILIARY DYSKINESIA (IMMOTILE CILIA SYNDROME, KARTAGENER SYNDROME)406 PULMONARY HEMOSIDEROSIS407 PULMONARY EMBOLISM, INFARCTION, AND HEMORRHAGE408 ATELECTASIS409 PULMONARY TUMORS410 PLEURISY, PLEURAL EFFUSIONS, AND EMPYEMA411 PNEUMOTHORAX412 PNEUMOMEDIASTINUM413 HYDROTHORAX414 HEMOTHORAX415 CHYLOTHORAX416 BRONCHOPULMONARY DYSPLASIA417 SKELETAL DISEASES INFLUENCING PULMONARY FUNCTION418 CHRONIC SEVERE RESPIRATORY INSUFFICIENCY419 EXTRAPULMONARY DISEASES WITH PULMONARY MANIFESTATIONSPART XXThe Cardiovascular System420 CARDIAC DEVELOPMENT422 HISTORY AND PHYSICAL EXAMINATION423 LABORATORY EVALUATIONSection 3 CONGENITAL HEART DISEASEDISEASE426 ACYANOTIC CONGENITAL HEART DISEASE: ? LEFT-TO-RIGHT SHUNT LESIONS427 ACYANOTIC CONGENITAL HEART DISEASE: ?OBSTRUCTIVE LESIONS428 ACYANOTIC CONGENITAL HEART DISEASE: REGURGITANT LESIONSNEONATE WITH CYANOSIS AND RESPIRATORY DISTRESS430 CYANOTIC CONGENITAL HEART LESIONS: LESIONS ASSOCIATED WITH DECREASED PULMONARY BLOOD FLOW431 CYANOTIC CONGENITAL HEART DISEASE: LESIONS ASSOCIATED WITH INCREASED PULMONARY BLOOD FLOW432 OTHER CONGENITAL HEART AND VASCULAR MALFORMATIONS433 PULMONARY HYPERTENSIONSection 4 CARDIAC ARRHYTHMIAS436 SUDDEN DEATHSection 5 ACQUIRED HEART DISEASE437 INFECTIVE ENDOCARDITIS438 RHEUMATIC HEART DISEASESection 7 CARDIAC THERAPEUTICS442 HEART FAILURE443 PEDIATRIC HEART AND HEART-LUNG TRANSPLANTATION445 SYSTEMIC HYPERTENSIONPART XXIDiseases of the BloodSection 1 THE HEMATOPOIETIC SYSTEM447 THE ANEMIAS448 CONGENITAL HYPOPLASTIC ANEMIA (DIAMONDBLACKFAN ANEMIA)449 PEARSON SYNDROME450 ACQUIRED PURE RED BLOOD CELL ANEMIA452 CONGENITAL DYSERYTHROPOIETIC ?ANEMIAS454 MEGALOBLASTIC ANEMIAS455 IRON-DEFICIENCY ANEMIA456 OTHER MICROCYTIC ANEMIASSection 3 HEMOLYTIC ANEMIAS458 HEREDITARY SPHEROCYTOSIS459 HEREDITARY ELLIPTOCYTOSIS460 HEREDITARY STOMATOCYTOSIS461 PAROXYSMAL NOCTURNAL HEMOGLOBINURIA AND ACANTHOCYTOSIS462 HEMOGLOBINOPATHIES463 ENZYMATIC DEFECTS464 HEMOLYTIC ANEMIAS RESULTING FROM EXTRACELLULAR FACTORS-IMMUNE HEMOLYTIC ANEMIASSection 4 POLYCYTHEMIA (ERYTHROCYTOSIS)466 POLYCYTHEMIA467 NON-CLONAL POLYCYTHEMIASection 5 THE PANCYTOPENIAS468 THE INHERITED PANCYTOPENIAS469 THE ACQUIRED PANCYTOPENIASSection 6 BLOOD COMPONENT TRANSFUSIONS470 RED BLOOD CELL TRANSFUSIONS AND ERYTHROPOIETIN THERAPY471 PLATELET TRANSFUSIONS472 NEUTROPHIL (GRANULOCYTE) TRANSFUSIONS473 PLASMA TRANSFUSIONSSection 7 HEMORRHAGIC AND THROMBOTIC DISEASES475 HEMOSTASIS476 HEREDITARY CLOTTING FACTOR DEFICIENCIES (BLEEDING DISORDERS)477 VON WILLEBRAND DISEASE480 POSTNEONATAL VITAMIN K DEFICIENCY481 LIVER DISEASE483 DISSEMINATED INTRAVASCULAR COAGULATION484 PLATELET AND BLOOD VESSEL DISORDERSSection 8 THE SPLEEN486 SPLENOMEGALY487 HYPOSPLENISM, SPLENIC TRAUMA, AND SPLENECTOMYSection 9 THE LYMPHATIC SYSTEM490 LYMPHADENOPATHYPART XXIICancer and Benign Tumors495 THE LEUKEMIAS496 LYMPHOMA498 NEUROBLASTOMA500 SOFT TISSUE SARCOMAS502 RETINOBLASTOMA503 GONADAL AND GERM CELL NEOPLASMS505 BENIGN VASCULAR TUMORS506 RARE TUMORSPART XXIIINephrologySection 1 GLOMERULAR DISEASESection 2 CONDITIONS PARTICULARLY ASSOCIATED WITH HEMATURIA510 ISOLATED GLOMERULAR DISEASES WITH RECURRENT GROSS HEMATURIA511 GLOMERULONEPHRITIS ASSOCIATED WITH INFECTIONS512 MEMBRANOUS NEPHROPATHY513 MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS514 GLOMERULONEPHRITIS ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOSUS515 HENOCH-SCHOENLEIN PURPURA NEPHRITIS516 RAPIDLY PROGRESSIVE (CRESCENTIC) GLOMERULONEPHRITIS517 GOODPASTURE DISEASE518 HEMOLYTIC-UREMIC SYNDROME520 HEMATOLOGIC DISEASES CAUSING HEMATURIA521 ANATOMIC ABNORMALITIES ASSOCIATED WITH HEMATURIASection 3 CONDITIONS PARTICULARLY ASSOCIATED WITH PROTEINURIA524 TRANSIENT PROTEINURIA525 ORTHOSTATIC (POSTURAL) PROTEINURIA526 FIXED PROTEINURIA527 NEPHROTIC SYNDROMESection 4 TUBULAR DISORDERS528 TUBULAR FUNCTION529 RENAL TUBULAR ACIDOSIS530 NEPHROGENIC DIABETES INSIPIDUS531 BARTTER AND GITELMAN SYNDROMES AND OTHER INHERITED TUBULAR TRANSPORT ABNORMALITIES532 TUBULOINTERSTITIAL NEPHRITISSection 5 ACUTE KIDNEY INJURY AND CHRONIC KIDNEY DISEASE533 TOXIC NEPHROPATHY534 CORTICAL NECROSIS535 RENAL FAILURE536 RENAL TRANSPLANTATIONPART XXIVUrologic Disorders in Infants and Children538 URINARY TRACT INFECTIONS539 VESICOURETERAL REFLUX542 NEUROPATHIC BLADDER543 ENURESIS AND VOIDING DYSFUNCTION547 URINARY LITHIASISPART XXVGynecologic Problems of Childhood548 HISTORY AND PHYSICAL EXAMINATION549 VULVOVAGINITIS550 BLEEDING551 BREAST CONCERNS552 POLYCYSTIC OVARY SYNDROME AND HIRSUTISM553 NEOPLASMS AND ADOLESCENT SCREENING FOR HUMAN PAPILLOMAVIRUS554 VULVOVAGINAL AND MUELLERIAN ANOMALIES555 GYNECOLOGIC CARE FOR GIRLS WITH SPECIAL NEEDSPART XXVIThe Endocrine System557 HYPOPITUITARISM558 DIABETES INSIPIDUS560 HYPERPITUITARISM, TALL STATURE, AND OVERGROWTH SYNDROMES563 THYROID DEVELOPMENT AND PHYSIOLOGY565 HYPOTHYROIDISM566 THYROIDITIS567 GOITER568 HYPERTHYROIDISM571 HYPOPARATHYROIDISM572 PSEUDOHYPOPARATHYROIDISM (ALBRIGHT HEREDITARY OSTEODYSTROPHY)573 HYPERPARATHYROIDISM575 ADRENOCORTICAL INSUFFICIENCY576 CONGENITAL ADRENAL HYPERPLASIA AND RELATED DISORDERS577 CUSHING SYNDROME578 PRIMARY ALDOSTERONISM579 ADRENOCORTICAL TUMORS580 PHEOCHROMOCYTOMA581 ADRENAL MASSES585 GYNECOMASTIA589 DIABETES MELLITUSPART XXVIIThe Nervous System590 NEUROLOGIC EVALUATION592 DEFORMATIONAL PLAGIOCEPHALY594 CONDITIONS THAT MIMIC SEIZURES595 HEADACHES596 NEUROCUTANEOUS SYNDROMES597 MOVEMENT DISORDERS598 ENCEPHALOPATHIES601 PEDIATRIC STROKE602 CENTRAL NERVOUS SYSTEM VASCULITIS603 CENTRAL NERVOUS SYSTEM INFECTIONS604 BRAIN ABSCESS605 IDIOPATHIC INTRACRANIAL HYPERTENSION/PSEUDOTUMOR CEREBRI606 SPINAL CORD DISORDERSPART XXVIIINeuromuscular Disorders607 EVALUATION AND INVESTIGATION609 MUSCULAR DYSTROPHIES610 ENDOCRINE AND TOXIC MYOPATHIES611 METABOLIC MYOPATHIES613 HEREDITARY MOTOR-SENSORY NEUROPATHIES614 TOXIC NEUROPATHIES615 AUTONOMIC NEUROPATHIES616 GUILLAIN-BARRE SYNDROME617 BELL PALSYPART XXIXDisorders of the Eye618 GROWTH AND DEVELOPMENT632 CHILDHOOD GLAUCOMA633 ORBITAL ABNORMALITIES634 ORBITAL INFECTIONSPART XXXThe Ear636 GENERAL CONSIDERATIONS AND EVALUATION637 HEARING LOSS638 CONGENITAL MALFORMATIONS639 EXTERNAL OTITIS (OTITIS EXTERNA)640 OTITIS MEDIAPART XXXIThe Skin648 CUTANEOUS DEFECTS649 ECTODERMAL DYSPLASIAS650 VASCULAR DISORDERS651 CUTANEOUS NEVI652 HYPERPIGMENTED LESIONS653 HYPOPIGMENTED LESIONS654 VESICULOBULLOUS DISORDERS655 ECZEMATOUS DISORDERS656 PHOTOSENSITIVITY665 CUTANEOUS BACTERIAL INFECTIONS666 CUTANEOUS FUNGAL INFECTIONS667 CUTANEOUS VIRAL INFECTIONS668 ARTHROPOD BITES AND INFESTATIONS669 ACNE671 NUTRITIONAL DERMATOSESPART XXXIIBone and Joint DisordersSection 1 ORTHOPEDIC PROBLEMS672 GROWTH AND DEVELOPMENT674 THE FOOT AND TOES675 TORSIONAL AND ANGULAR DEFORMITIES676 LEG-LENGTH DISCREPANCY677 THE KNEE678 THE HIP679 THE SPINE680 THE NECK681 THE UPPER LIMB682 ARTHROGRYPOSIS683 COMMON FRACTURES684 OSTEOMYELITIS685 SEPTIC ARTHRITISSection 2 SPORTS MEDICINE688 SPORTS-RELATED TRAUMATIC BRAIN INJURY (CONCUSSION)689 CERVICAL SPINAL INJURIES690 HEAT INJURIES692 PERFORMANCE-ENHANCING AIDS693 SPECIFIC SPORTS AND ASSOCIATED ?INJURIESSection 3 THE SKELETAL DYSPLASIAS694 GENERAL CONSIDERATIONS695 DISORDERS INVOLVING CARTILAGE MATRIX PROTEINS696 DISORDERS INVOLVING TRANSMEMBRANE RECEPTORS697 DISORDERS INVOLVING ION TRANSPORTERS698 DISORDERS INVOLVING TRANSCRIPTION FACTORS699 DISORDERS INVOLVING DEFECTIVE BONE RESORPTION701 OSTEOGENESIS IMPERFECTA702 MARFAN SYNDROMESection 4 METABOLIC BONE DISEASE703 BONE STRUCTURE, GROWTH, AND HORMONAL REGULATION704 PRIMARY CHONDRODYSTROPHY (METAPHYSEAL DYSPLASIA)705 HYPOPHOSPHATASIA706 HYPERPHOSPHATASIA707 OSTEOPOROSISPART XXXIIIRehabilitation Medicine710 SEVERE TRAUMATIC BRAIN INJURY711 SPINAL CORD INJURY AND AUTONOMIC CRISIS MANAGEMENT712 SPASTICITY713 BIRTH BRACHIAL PLEXUS PALSY715 MENINGOMYELOCELE (SPINA BIFIDA)716 AMBULATION ASSISTANCE717 HEALTH AND WELLNESS FOR CHILDREN WITH DISABILITIESPART XXXIVEnvironmental Health Hazards719 CHEMICAL POLLUTANTS720 HEAVY METAL INTOXICATION721 LEAD POISONING722 NONBACTERIAL FOOD POISONING723 BIOLOGIC AND CHEMICAL TERRORISM724 ANIMAL AND HUMAN BITES725 ENVENOMATIONSPART XXXVLaboratory Medicine727 REFERENCE INTERVALS FOR LABORATORY TESTS AND PROCEDURES
