基本説明
This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage. Previous ed.: 2008.
Full Description
Fundamental Immunology
Seventh Edition
This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed.
Look inside and discover...
• Fully revised and updated content reflects the latest advances in the field.
• Current insights enhance readers' understanding of immune system function
• Unique approach bridges the gap between basic immunology and the disease process.
• Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment.
• Abundant illustrations and tables deliver essential information at a glance.
PLUS...
A convenient companion website features the fully searchable text with all references linked to PubMed.
Pick up your copy today!
Contents
Section I. Introduction to Immunology
1 The Immune System
William E. Paul
2 History of Immunology
Steven Greenberg
Section II. Organization and Evolution of the Immune System
3 Lymphoid Tissues and Organs
Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle
4 Evolution of the Immune System
Martin F. Flajnik
Section III. Immunoglobulins and B Lymphocytes
5 Immunoglobulins: Structure and Function
Harry W. Schroeder
6 Immunoglobulins: Molecular Genetics
Edward E. Max and Sebastian Fugmann
7 Antigen-Antibody Reactions
Jay A. Berzofsky and Ira Berkower
8 B Lymphocyte Development
Richard R. Hardy
9 B Lymphocyte Receptors, Signaling Mechanisms, and Activation
Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce
10 B Lymphocyte Responses
Michael McHeyzer-Williams
Section IV. T Lymphocytes
11 T Lymphocyte Receptors
Mark M. Davis
12 T Lymphocyte Signaling Mechanisms
Takashi Saito
13 T Lymphocyte Developmental Biology
Ellen V. Rothenberg and Ameya Champhekar
14 Peripheral T Lymphocyte Responses and Function
Marc K. Jenkins
Section V. The Intersection of Innate and Adaptive Immunity
15 The Innate Immune System
Luke A. J. O'Neill
16 Dendritic Cells
Michel C. Nussenzweig
17 Natural Killer Cells
Wayne M. Yokoyama
18 CD1d-restricted NKT Cells
Albert S. Bendelac
19 Macrophages and Phagocytosis
Siamon Gordon
20 Granulocytes and Mast Cells
Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella
21 The Major Histocompatibility Complex and its Proteins
David H. Margulies
22 Antigen Processing and Presentation
Ted H. Hansen and Paul A. Roche
Section VI. Induction, Regulation, and Effector Functions of the Immune Response
23 Immunogenicity and Antigen Structure
Jay A. Berzofsky
24 Fc Receptors and Their Role in Immune Regulation and Inflammation
Jeffrey V. Ravetch and Falk Nimmerjahn
25 Type I Cytokines and Interferons
Warren J. Leonard
26 Interleukin-1 Family Cytokines
Charles A. Dinarello and Mihai G. Netea
27 TNF-related Cytokines in Immunity
Carl F. Ware
28 Chemokines
Philip M. Murphy
29 Helper T Cell Differentiation and Plasticity
John J. O'Shea
30 Programmed Cell Death
Andrew L. Snow and Michael J. Lenardo
31 Immunological Memory
Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger
32 Immunological Tolerance
Pamela S. Ohashi
33 Regulatory/Suppressor T Cells
Ethan M. Shevach
34 Mucosal Immunity and Microbiome
Yasmine Belkaid
35 Neurophysiological Reflex Mechanisms in Immunology
Chavan and Kevin J. Tracey
36 Complement
B. Paul Morgan
37 Cell-mediated Cytotoxicity
Judy Lieberman
Section VII. Immunity to Infectious Agents
38 The Immune Response to Parasites
Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley
39 Immunity to Viruses
Hildegund C.J. Ertl
40 Immunity to Intracellular Bacteria
Anca Dorhoi, Stephen T. Reece, and Stefan H. E. Kaufmann
41 Immunity to Extracellular Bacteria
Moon H. Nahm and Jannet Katz
42 Immunology of HIV Infection
Bruce Walker
43 Vaccines
Ennio De Gregorio, Ugo D'Oro, Sylvie Bertholet, and Rino Rappuoli
Section VIII. Immunologic Mechanisms in Disease
44 Organ-Specific Autoimmunity
Ken T. Coppieters, Matthias G. von Herrath, and Dirk Homann
45 Allergy
Marsha Wills-Karp
46 Transplantation Immunology
Megan Sykes
47 Cancer Immunology
Hans Schreiber
48 Inborn Errors of Immunity
Jean-Laurent Casanova, Mary Ellen Conley, and Luigi D. Notarangelo
