Introduction to Evolutionary Genomics (Computational Biology)

Saitou, Naruya

Springer London Ltd（2016/08発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 461 p.
• 言語 ENG
• 商品コード 9781447171591
• DDC分類 572.86

Full Description

This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

Contents

Part I: Basic Processes of Genome Evolution.- Basic Metabolism Surrounding DNAs.- Mutation.- Phylogeny.- Neutral Evolution.- Natural Selection.- Part II: Evolving Genomes.- Brief History of Life.- Prokaryote Genomes.- Eukaryote Genomes.- Vertebrate Genomes.- Human Genomes.- Part III: Methods for Evolutionary Genomics.- Genome Sequencing.- Omic Data Collection.- Databases.- Sequence Homology Handling.- Evolutionary Distances.- Tree and Network Building.- Population Genomics.