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Full Description
Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.
A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.
Topics Include
Nail anatomy, physiology, diseases, and treatment
Permeability of the nail plate
Topical nail formulations
Approaches to enhance ungual and trans-ungual drug delivery
In vitro and in vivo models to evaluate topical nail formulations
Nail sampling techniques
Bioengineering of the nail
Trans-ungual iontophoresis
Pharmacokinetics of drugs in the nail apparatus
Onychopharmacokinetics: proposed model insight
Photodynamic therapy of nail diseases
The nail as a surrogate for investigating drug use
Contents
The Nail: Anatomy, Physiology, Diseases, and Treatment. Permeability of the Nail Plate. Topical Nail Formulations. Approaches to Enhance Ungual and Trans-Ungual Drug Delivery. In Vitro and In Vivo Models to Evaluate Topical Nail Formulations. Hydration-Controlled Nail System for the Evaluation of Topical Formulations and a Novel Nail Sampling Device. Bioengineering of the Nail: Transonychial Water Loss and Imaging Techniques, An Overview. Transungual Iontophoresis and Physical Drug Delivery Enhancement. Pharmacokinetics of Drugs in the Nail Apparatus. Onychopharmacokinetics: Proposed Model Insight. Photodynamic Therapy of Nail Diseases. Nail as a Surrogate for Investigating the Drug Use.
