基本説明
Provides state-of-the-art information on all aspects of Parkinson's disease.
Full Description
In recent years, considerable advances have been made in our knowledge and understanding of Parkinson's disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances implemented. Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD.
Contents
OverviewJames ParkinsonJennifer G. Goldman and Christopher G. GoetzParkinson's Disease: Where Have We Been?Lawrence W. ElmerParkinson's Disease: Where Are We?Raul de la Fuente-FernandezEpidemiologyEpidemiology of Parkinson's Disease: An OverviewMonica Korell and Caroline M. TannerEnvironmental Toxins and Parkinson's DiseaseJason R. Cannon and Timothy J. GreenamyreRural Environment and Parkinson's DiseaseDaniel StricklandIndustrial and Occupational Exposures and Parkinson DiseaseSamuel GoldmanTetrahydroisoquinolines and Parkinson's DiseaseMark S. LeDouxEndogenous Neurotoxins in the Pathogenesis and Progression of Parkinson's DiseaseShaik Shavali and Manuchair EbadiGeneticsOverview of the Genetics of ParkinsonismMathias Toft and Zbigniew K. Wszolek-Synuclein and Parkinson's DiseaseThomas GasserLRRK2-Associated Parkinson's DiseaseJonathan Carr and Soraya BardienParkin-Associated Parkinson's DiseaseAnne Grunewald and Christine KleinPINK1- and DJ-1-Linked ParkinsonismEng-King TanGenetic and Bioinformatic Tools in Parkinson's DiseaseTatiana Foroud and Nathan PankratzClinical Features of Parkinson's DiseaseTremor, Rigidity, and BradykinesiaKelvin L. Chou and Howard I. HurtigGait Disorders in Parkinson's DiseaseYacov Balash, Jeffrey M. Hausdorff, Tanya Gurevich, and Nir GiladiSomesthesiaPadraig O'SuilleabhainPain in Parkinson's DiseaseBlair FordRestless Legs Syndrome and Periodic Limb Movements of SleepBryan T. Klassen and Charles H. AdlerFatigue: A Common Comorbidity in Parkinson's DiseaseAnelyssa D'Abreu and Joseph H. FriedmanVisual Dysfunction in Parkinson's DiseaseRobert L. RodnitzkyVisuo-Cognitive Dysfunctions in Parkinson's DiseaseAndrea Antal, Walter Paulus, and Ivan Bodis-WollnerOlfactory Dysfunction in Parkinson's Disease and Parkinsonian SyndromesKaterina Markopoulou and Bruce A. ChaseInsomnia and Excessive Daytime Sleepiness in Parkinson's DiseaseJ.A. Van Gerpen and Pablo CastilloREM Sleep Behavior DisorderAleksandar Videnovic and Cynthia L. ComellaGastrointestinal Dysfunction in Parkinson's DiseaseRonald F. PfeifferUrological DysfunctionCarlos Singer and Henry MooreSexual DysfunctionCheryl Waters and Janice SmolowitzCardiovascular Autonomic Dysfunction in Parkinson's Disease and Parkinsonian SyndromesValeria Iodice, David Low, Ekawat Vichayanrat, and Christopher J. MathiasDisorders of Thermoregulation in Parkinson's DiseaseThomas L. DavisRespiratory DysfunctionHolly ShillDepression in Parkinson's DiseaseSteven P. Wengel, Dennis P. McNeilly, and William J. BurkeAnxiety and Parkinson DiseaseJeremy Quickfall, Michael Trew, and Oksana SuchowerskyApathy in Parkinson's DiseaseHoward D. Weiss and Laura MarshDementiaAnne L. Barba, B. Kelly Changizi, Donald S. Higgins, Stewart A. Factor, and Eric S. MolhoPathophysiology of Parkinson's DiseaseAnimal Models of Basal Ganglia Injury and Degeneration and Their Application to Parkinson's Disease ResearchGiselle M. Petzinger and Michael W. JakowecNeuroanatomy of Parkinson's DiseaseHeiko Braak and Kelly Del Tredici-BraakNeuropathology of Parkinson's DiseaseJohn E. Duda and Dennis W. DicksonNeurophysiology of the Motor Disorder in Parkinson's DiseaseGaetan Garraux and Mark HallettNeurochemistry of Parkinson's Disease: DopamineL. Charles MurrinPathophysiology of Parkinson's Disease, Neurochemical Pathology: Other NeurotransmittersYoshikuni MizunoTheories of PathogenesisOxidative StressCasey Cook and Leonard PetrucelliMitochondrial DysfunctionDaniel G. Healy and A.H.V. SchapiraExcitotoxicityFabio BlandiniInflammationRoger KurlanProtein Conformational and Metabolic Changes in Parkinson's DiseaseKevin St. P. McNaught and C. Warren OlanowCell Death in Parkinson's DiseaseShankar Sadasivan, Ane Korff, Ciaran J. Faherty, and Richard Jay SmeyneDiagnosis of Parkinson's DiseaseDifferential Diagnosis of Parkinson's DiseaseSerena W. Hung and Anthony E. LangNeuroleptic-Induced Movement DisordersManuchair EbadiClinical Diagnostic Criteria for Parkinson's DiseaseDaniel Tarsy and Laurie GordonClinical Batteries and Biomarkers in the Diagnosis of Parkinson's DiseaseClaire Henchcliffe and Un KangRating ScalesKathleen M. ShannonMR Imaging of ParkinsonismJames B. WoodMolecular Imaging in Parkinson DiseaseDanna Jennings, David Russell, Ken Marek, and John SeibylPositron Emission Tomography in Parkinson's DiseaseSilke Appel-Cresswell, R. Nandhagopal, John R. Adams, and A. Jon StoesslTranscranial Ultrasound in Parkinson's DiseaseDaniela Berg, Bettina Faust, and Alexandra GaenslenIn Vivo Molecular Imaging in Parkinson's DiseaseSushil K. Sharma and Manuchair EbadiPlacebo Effect in Parkinson's DiseaseJayasri Srinivasan, Sarah C. Lidstone, Raul de la Fuente-Fernandez, and A. Jon StoesslTreatment of Parkinson's Disease with Anticholinergic MedicationsDuarte Machado and Bahman JabbariAmantadineKelly E. Lyons and Rajesh PahwaMAO-B Inhibitors for the Treatment of Parkinson's DiseaseJohn BertoniCatechol-O-Methyltransferase Inhibitors in the Treatment of Parkinson's DiseaseMervat Wahba, Theresa A. Zesiewicz, and Robert A. HauserSymptomatic Treatment of Parkinson's Disease: LevodopaJohn L. Goudreau and J. Eric AhlskogDopamine Agonists in Parkinson's DiseaseJoseph Jankovic and Toby C. YalthoNon-Dopaminergic Drugs for Motor SymptomsPierre R. Burkhard and Francois J.G. VingerhoetsStereotactic Ablative Procedures for Intractable Parkinson's DiseaseMarco Sassi and Michael S. OkunDeep Brain Stimulation SurgeryRyan J. Uitti, Yashiko Baba, and Robert E. Wharen Jr.Neurotransplantation in the Treatment of Parkinson's DiseasePenelope Hallett and Ole IsacsonRole of Physical Therapy in Management of Parkinson's DiseaseRose WichmannSpeech Therapy in the Treatment of Parkinson's DiseaseShimon Sapir, Lorraine Ramig, and Cynthia FoxDysphagia in Parkinson's DiseaseLisa A. NewmanRestorative and Functional Occupational Therapy in Parkinson's DiseaseSurya ShahNeurologic Music Therapy: A Modality to Address the Diverse Needs of People with Parkinson's DiseaseSandra L. HoltenDance for Persons with Parkinson's Disease*Olie WestheimerPathogenesis of Motor Response Complications in Parkinson's Disease: "Mere Conjectural Suggestions" and BeyondLeo Verhagen Metman and Christina L. VaughanTreatment of Early Parkinson's DiseaseJohn C. Morgan and Kapil D. SethiTreatment of Moderate Parkinson's DiseaseJohn E. Duda and Matthew B. SternManagement of Advanced Parkinson's DiseaseGrace S. Lin Liang and James W. TetrudRole and Design of Clinical Trials for Parkinson's DiseaseAndrew Siderowf and Stanley FahnFuture Symptomatic Therapy in Parkinson's DiseaseRuth Djaldetti, Shlomit Yust-Katz, and Eldad MelamedCalcium Influx, Free Radicals, and Aging: A Metabolic Burden Linked to Neuronal Loss in Parkinson's DiseaseJavier Sanchez-Padilla, Jaime N. Guzman, and D. James SurmeierTherapeutic Potential of Exercise in Parkinson's DiseaseBrian K. SchillingGene Therapy for Parkinson's: Disease from Bench to BedsideFredric P. Manfredsson, Aaron C. Rising, M. Angela Cenci, Carmen S. Peden, and Ronald J. MandelTranslating Stem Cell Biology to Regenerative Medicine for Parkinson's DiseaseFlorian A. Siebzehnrubl and Dennis A. SteindlerAlternative Drug Delivery in the Treatment of Parkinson's DiseasePierre J. BlanchetEconomics of Parkinson's DiseaseJessica Mastalski, Robert G. Holloway, and Katia NoyesInformal Caregiving: An Essential Part of the TeamCarmen Dyck and Susan M. CalneDriving in Parkinson's DiseaseErgun Y. UcEvolution and Potential of the National Parkinson's Organizations: A Brief OverviewRuth A. HagestuenComprehensive Parkinson's Disease Care in Complex EnvironmentsElaine Cohen, Monique Giroux, Ruth A. Hagestuen, and Gladys Gonzalez-RamosIndex
