Full Description
This practical, user-friendly, and informative text surveys basic principles of toxicology. It is an invaluable guide to evaluating toxicity and related data, approaching toxicity testing and interpretation, and understanding the concepts of hazard prediction and risk assessment and management.A Guide to Practical Toxicology:examines how to evaluate various groups of chemicals-pharmaceuticals, cosmetics, and agrochemicalsprovides insights on toxicity determination, normality and naturality, prediction, and regulationTwo all-new chapters cover:safety pharmacologyevaluation of different chemical classes
Contents
Introduction to toxicologydefinition and maintenance. Determination of toxicity: basic principles. Determination of toxicity in vitro. Safety Pharmacology. Determination: general and reproductive toxicology. Determination: genotoxicity and carcinogenicity. Determination: irritation and sensitization. Determination: environmental toxicology and epidemiology. Interpretation. Prediction of hazard. Background to risk due to toxicity. Risk assessment in practice and setting exposure limits. Risk assessment and management in the workplace. Risk assessment: carcinogenicity; the environment; evolution and overview of risk assessment. Evaluation of specific groups of chemicals. The future of toxicity testing.
